DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33253 and Stoml2

DIOPT Version :9

Sequence 1:	NP_001259699.1	Gene:	CG33253 / 2768889	FlyBaseID:	FBgn0030992	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_075720.1	Gene:	Stoml2 / 66592	MGIID:	1913842	Length:	353	Species:	Mus musculus

Alignment Length:	272	Identity:	74/272 - (27%)
Similarity:	133/272 - (48%)	Gaps:	53/272 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 PISVFICFKVVSEYERAVIFRMGRLRSGGARGPGVFFVLPCVDDY-YPVDLRTVSFDVPPQEVLS 149
            |.:..|.|  |.:.|..|:.||||...  ...||:..::|.:|.. |...|:.:..:||.|..::
Mouse    33 PRNTVILF--VPQQEAWVVERMGRFHR--ILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVT 93

  Fly   150 KDSVTVTVDAVVYYRISDPLKAVIQVYNYSHSTSLLAATTLRNVLGTRNLSELLTERETISHTMQ 214
            .|:||:.:|.|:|.||.||.||...|.:..::.:.||.||:|:.||..:|.::..|||:::..:.
Mouse    94 LDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIV 158

  Fly   215 MSLDEATDPWGVKVERVEIKDVSLPTALQRAMAAEAEAAREARAKVIAAEGEMKS---------- 269
            .::::|.|.||::..|.||||:.:|..::.:|..:.||.|..||.|:.:||..:|
Mouse   159 DAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQ 223

  Fly   270 --------------SRALREASEIIS---ASPSALQL--------------------RYLQTLSS 297
                          ::|..|||.:::   |...|:::                    :|:...|.
Mouse   224 AQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNGDAAASLTVAEQYVSAFSK 288

  Fly   298 ISTEKNSTIIFP 309
            ::.:.| |::.|
Mouse   289 LAKDSN-TVLLP 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33253	NP_001259699.1	PHB	92..239	CDD:214581	50/147 (34%)
CG33253	NP_001259699.1	SPFH_SLP-4	112..319	CDD:259813	64/246 (26%)
Stoml2	NP_075720.1	HflC	38..314	CDD:223407	73/267 (27%)
		SPFH_paraslipin	74..184	CDD:259811	38/109 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810