Protein Alignment CG33253 and PHB

DIOPT Version :9

• Sequence 1: NP_001259699.1
• Gene: CG33253 / 2768889
• FlyBaseID: FBgn0030992
• Length: 414
• Species: Drosophila melanogaster
• Sequence 2: NP_001268425.1
• Gene: PHB / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 61/243 - (25%)
• Similarity: 107/243 - (44%)
• Gaps: 38/243 - (15%)

  Fly   101 RAVIFRMGRLRSGGARGPGVFFVLPCVDDYYPVDLRTVSFDVPPQEVL--SKDSVTVTVDAVVYY 163
            |||||...|.......|.|..|::|.|......|.|:...:||   |:  |||...|.:...:.:
Human    35 RAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVP---VITGSKDLQNVNITLRILF 96

  Fly   164 R-ISDPLKAVIQVYNYSHSTSLLAATT---LRNVLGTRNLSELLTERETISHTMQMSLDEATDPW 224
            | ::..|..:.......:...:|.:.|   |::|:...:..||:|:||.:|..:...|.|....:
Human    97 RPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATF 161

  Fly   225 GVKV---------------ERVEIKDVSLPTALQRAMAAEAEAAREARAKVIAAEGEMKSSRALR 274
            |:.:               |.||.|.|:...| :||.....:|.::.:|.:|:|||:.|::..:
Human   162 GLILDDVSLTHLTFGKEFTEAVEAKQVAQQEA-ERARFVVEKAEQQKKAAIISAEGDSKAAELI- 224

  Fly   275 EASEIISASPSALQLRYLQTLSSI----STEKNST-------IIFPLP 311
             |:.:.:|....::||.|:....|    |..:|.|       ::..||
Human   225 -ANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33253	NP_001259699.1	PHB	92..239	CDD:214581	40/158 (25%)
		SPFH_SLP-4	112..319	CDD:259813	55/232 (24%)
PHB	NP_001268425.1	SPFH_prohibitin	27..221	CDD:259799	50/189 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810