Protein Alignment CG33253 and nphs2

DIOPT Version :10

• Sequence 1: NP_001259699.1
• Gene: CG33253 / 2768889
• FlyBaseID: FBgn0030992
• Length: 414
• Species: Drosophila melanogaster
• Sequence 2: XP_017949096.1
• Gene: nphs2 / 100498000
• XenbaseID: XB-GENE-485101
• Length: 376
• Species: Xenopus tropicalis
• Alignment Length: 277
• Identity: 123/277 - (44%)
• Similarity: 182/277 - (65%)
• Gaps: 8/277 - (2%)

  Fly    58 LKTSENDD------MGCVEILATVVSVLIMVLTFPISVFICFKVVSEYERAVIFRMGRLRSGGAR 116
            |:||:.||      ....|.|.....:|:::||.|:|::.|.|||.|||||||||:||:.||.||
 Frog    78 LETSQKDDGVKPAGFRVFEGLLIFCCLLLVILTLPLSIWFCVKVVREYERAVIFRLGRMLSGRAR 142

  Fly   117 GPGVFFVLPCVDDYYPVDLRTVSFDVPPQEVLSKDSVTVTVDAVVYYRISDPLKAVIQVYNYSHS 181
            |||:||.|||:|..:.||.|..:|:||..::::||.||:.:|.:.|||:.:....:..|.:.|.:
 Frog   143 GPGLFFYLPCLDKCHKVDFRLKTFEVPFHQIVTKDLVTLEIDVICYYRLENACLFLTSVSSISSA 207

  Fly   182 TSLLAATTLRNVLGTRNLSELLTERETISHTMQMSLDEATDPWGVKVERVEIKDVSLPTALQRAM 246
            ..||..||.:.:|..|...::|.||::|...::::||.||..||:||||.|||||.||..::::|
 Frog   208 FQLLVQTTTKRLLAHRAFLDILLERKSIGEEVKVALDAATCHWGIKVERTEIKDVKLPEEVKQSM 272

  Fly   247 AAEAEAAREARAKVIAAEGEMKSSRALREASEIISASPSALQLRYLQTLSSISTEKNSTIIFPLP 311
            |.||||.|.|:.||||||||...|..::.|:|.:|.||:|:|||||.||..:::||.:|.:.|||
 Frog   273 AVEAEAQRHAKVKVIAAEGEKTVSEYIKLAAEKLSGSPTAIQLRYLHTLQCMTSEKPATFVLPLP 337

  Fly   312 MELLTPFLNTQAHSQQL 328
            .:|:.  ||..|...::
 Frog   338 FDLMN--LNAVARLPEI 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33253	NP_001259699.1	SPFH_SLP-4	112..319	CDD:259813	93/206 (45%)
nphs2	XP_017949096.1	SPFH_podocin	116..338	CDD:259809	106/221 (48%)