DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sdic4 and sw

DIOPT Version :9

Sequence 1:	NP_001368966.1	Gene:	Sdic4 / 2768886	FlyBaseID:	FBgn0053499	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_477075.2	Gene:	sw / 44160	FlyBaseID:	FBgn0003654	Length:	663	Species:	Drosophila melanogaster

Alignment Length:	586	Identity:	516/586 - (88%)
Similarity:	522/586 - (89%)	Gaps:	55/586 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LRSTYSTLSGGKKQPLNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAF---------- 63
            |::|.:..|||||||||||||||||||||||||||||||||||||||||||||:.
  Fly    93 LQATVNGQSGGKKQPLNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLSCHSSPLSGYME 157

  Fly    64 --------------------------DAQGDDEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAP 102
                                      |...|||||||||||||||||||||||||||||||||||
  Fly   158 DWWRPRKAHATDYYDEYNLNPGLEWEDEFTDDEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAP 222

  Fly   103 AITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAGRVIERALSENVDIYTDYIGGGDS 167
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   223 AITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAGRVIERALSENVDIYTDYIGGGDS 287

  Fly   168 EEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGVVMVWNT 232
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   288 EEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGVVMVWNT 352

  Fly   233 KFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHP 297
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   353 KFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHP 417

  Fly   298 VYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAIAITSMAFPANEINSLV 362
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   418 VYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAIAITSMAFPANEINSLV 482

  Fly   363 MGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFLTSS----IKIWSLKL 423
            |||||||||||||||||||||||||||||||||||||||||||||||||||||    ||:||||
  Fly   483 MGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLK- 546

  Fly   424 PISSCQFSVVSGINSNKPLYSFEDNSDYMMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTA 488
                          ..||||||||||||:||||||||||||||||||||||||||||||||||||
  Fly   547 --------------DTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTA 597

  Fly   489 SIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEWSRFNTHLSEIKMNQSDE 553
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   598 SIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEWSRFNTHLSEIKMNQSDE 662

  Fly   554 V 554
            |
  Fly   663 V 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sdic4	NP_001368966.1	Dynein_IC2	23..51	CDD:402922	27/27 (100%)
		WD40	196..523	CDD:421866	307/330 (93%)
		WD40 repeat	196..245	CDD:293791	48/48 (100%)
		WD40 repeat	251..289	CDD:293791	37/37 (100%)
		WD40 repeat	298..337	CDD:293791	38/38 (100%)
		WD40 repeat	349..446	CDD:293791	78/100 (78%)
		WD40 repeat	452..490	CDD:293791	36/37 (97%)
		WD40 repeat	498..524	CDD:293791	25/25 (100%)
sw	NP_477075.2	Dynein_IC2	107..135	CDD:402922	27/27 (100%)
		WD40	316..632	CDD:421866	307/330 (93%)
		WD40 repeat	316..365	CDD:293791	48/48 (100%)
		WD40 repeat	371..409	CDD:293791	37/37 (100%)
		WD40 repeat	418..457	CDD:293791	38/38 (100%)
		WD40 repeat	469..555	CDD:293791	78/100 (78%)
		WD40 repeat	561..599	CDD:293791	36/37 (97%)
		WD40 repeat	607..633	CDD:293791	25/25 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439698
Domainoid	1	1.000	911	1.000	Domainoid score	I181
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37921
Inparanoid	1	1.050	624	1.000	Inparanoid score	I842
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54336
OrthoDB	1	1.010	-	-		D1453532at2759
OrthoFinder	1	1.000	-	-		FOG0001314
OrthoInspector	1	1.000	-	-		mtm6471
orthoMCL	1	0.900	-	-		OOG6_101571
Panther	1	1.100	-	-	P	PTHR12442
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X812
	12	11.910