DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sdic4 and Dnai2

DIOPT Version :9

Sequence 1:NP_001368966.1 Gene:Sdic4 / 2768886 FlyBaseID:FBgn0053499 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_001030050.2 Gene:Dnai2 / 432611 MGIID:2685574 Length:623 Species:Mus musculus


Alignment Length:478 Identity:118/478 - (24%)
Similarity:199/478 - (41%) Gaps:100/478 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    93 GLPTVKDVAPAITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAGRVIERALSEN--V 155
            |.|  |||    .|.|:::....:|:|.:           .||:...|::.|.::|..:.:|  :
Mouse    80 GWP--KDV----NPQELEQTIRFRKKVEK-----------DENYINAVMQLGSIMEHCIKQNNAI 127

  Fly   156 DIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPE----LVVG----- 211
            |||.:|....::.|..:|...|: ::| ||.|.:..| |..|.:.|   .|:    |.|.     
Mouse   128 DIYEEYFDDEEAVEVTEEAPSAK-TIN-VFRDPQEIK-RTATHLSW---HPDGNRKLAVAYSCLK 186

  Fly   212 -----------SYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNP---NLI 262
                       ||..:.|:||.|:       ...|..:|            ....::||   :::
Mouse   187 FQRAPMSMNYDSYIWDLENPNRPE-------IALKPLSP------------LVTLEYNPKDSHVL 232

  Fly   263 LGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLD 327
            |||.|:|||..||.|  |.:.:........:|..|||....:.::......|.|:||::..|.:.
Mouse   233 LGGCYNGQIACWDTR--KGSLVAELSTIEFSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIR 295

  Fly   328 MLSQPQDT----LELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEV--Y 386
            .:|:|.:.    :..:::...|:...|:.|.:......::|:|.|.|.|.:|.........|  :
Mouse   296 KISEPIEVVIMDISRKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTQAEKIVCTF 360

  Fly   387 ERHLGPITGISTHYNQLSPDFGHLFLTS---SIKIWSLKLPISSCQFSVVSGINSNKPLYSFEDN 448
            ..|.|||..:     |.:|.:...|||.   :.:|||.....||..::              :.:
Mouse   361 YGHHGPIYAL-----QRNPFYPKNFLTVGDWTARIWSEDSRESSIMWT--------------KYH 406

  Fly   449 SDYMMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVAGAPAL-NRVSWTPSGLHVCI 512
            ..|:.|.|||||.||:|......|.||:|:|......|..|:.|...|.. .||.  .:|..:..
Mouse   407 MAYLSDGAWSPVRPAVFFTTKMDGTLDIWDLVFKQCDPALSLKVCDDPLFCLRVQ--DNGCLIAC 469

  Fly   513 GDEAGKLYVYDVAENLAQPSRDE 535
            |.|.|...:.:|:.:|:...|:|
Mouse   470 GSELGTTTLLEVSSSLSTLQRNE 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sdic4NP_001368966.1 Dynein_IC2 23..51 CDD:402922
WD40 196..523 CDD:421866 86/359 (24%)
WD40 repeat 196..245 CDD:293791 13/68 (19%)
WD40 repeat 251..289 CDD:293791 13/40 (33%)
WD40 repeat 298..337 CDD:293791 9/42 (21%)
WD40 repeat 349..446 CDD:293791 23/101 (23%)
WD40 repeat 452..490 CDD:293791 15/37 (41%)
WD40 repeat 498..524 CDD:293791 6/26 (23%)
Dnai2NP_001030050.2 WD40 repeat 165..212 CDD:293791 11/56 (20%)
WD40 <166..495 CDD:225201 90/372 (24%)
WD 1 214..254 15/53 (28%)
WD40 repeat 220..259 CDD:293791 13/40 (33%)
WD 2 261..302 11/40 (28%)
WD40 repeat 266..361 CDD:293791 19/94 (20%)
WD40 repeat 318..351 CDD:293791 8/32 (25%)
WD 3 362..401 14/43 (33%)
WD40 repeat 367..403 CDD:293791 11/40 (28%)
WD 4 405..445 15/39 (38%)
WD40 repeat 410..435 CDD:293791 12/24 (50%)
WD 5 450..489 10/40 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 565..602
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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