DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sdic4 and CG13074

DIOPT Version :9

Sequence 1:	NP_001368966.1	Gene:	Sdic4 / 2768886	FlyBaseID:	FBgn0053499	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_648835.1	Gene:	CG13074 / 39760	FlyBaseID:	FBgn0036567	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	82/453 - (18%)
Similarity:	146/453 - (32%)	Gaps:	141/453 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 DSEEANDERSHAR-------LSLNRVFYDER----WSKNRC-------------ITSMDWST--- 203
            |:.....|:.|..       :|...|.||||    |.:..|             :..:..|.
  Fly    41 DAATGTQEKLHVATQTEQRVVSSKDVEYDERALAKWLRQICPMVERELMNPTPLMEDLTMSQCRL 105

  Fly   204 -------HFPELVVGSYHNNE--------ESPNEPDGVVMVWNT-------------KFKKSTPE 240
                   .:.:|::|...|::        .:.|.|   |:|..|             :.|...|:
  Fly   106 EEKLQVYTYQKLIMGGAENSQGLAIWLCVHTNNAP---VLVATTVAPHDDWCEHVDQQLKLFVPQ 167

  Fly   241 -------------DVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLW--------DNRV--QKRT 282
                         .....:|.:.|.|...||..:..|.|..|::.:|        |:.|  ::..
  Fly   168 RMSVGNLVIYTEAKTLPLKSCLRSLCTNPFNKTMFAGSTMDGELFIWLYEQARGSDSSVDIKQLY 232

  Fly   283 PIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAIA 347
            .:..|..:|.|...|          ..|.:::..::|.:..|.|..    |..|:.:......::
  Fly   233 SVSSTQGAAVALDWP----------REHLLLACFANGSVRQWDLSR----QMALDWEYTLPATVS 283

  Fly   348 ITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFL 412
            ....|.....::..|:|:.||.||.....|          |....|..|     :|.....|.|:
  Fly   284 SEPTAMVTLGLDDFVVGTNDGGVYRCWNTG----------RQTAAIKQI-----KLLALRRHRFM 333

  Fly   413 TSSIKIWSLK--LPISSCQFSVVSGINSNKPLYS-----FEDNSDYMMDVAWSPVHPALFAAVDG 470
            .|::....::  |.:.||..       |.:..|.     .||.:..::.:. .|....:..:.||
  Fly   334 VSTLLRTEMEGNLFVLSCDL-------SGQAFYHDMRLVDEDMAQLIVQIP-LPFKNVIACSRDG 390

  Fly   471 S--------GRLDLWNLNQDTEVPTASIVVAGAPALNRVS----WTPSGLHVCIGDEAGKLYV 521
            :        |.|:.:.::......... .:.|..:|.|.|    |..:||:   |||....||
  Fly   391 NIIFCPANDGSLEYYRVSDGAHAHVKG-GLRGKGSLIRSSDNGRWLIAGLY---GDEFQIFYV 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sdic4	NP_001368966.1	Dynein_IC2	23..51	CDD:402922
		WD40	196..523	CDD:421866	71/399 (18%)
		WD40 repeat	196..245	CDD:293791	11/92 (12%)
		WD40 repeat	251..289	CDD:293791	11/47 (23%)
		WD40 repeat	298..337	CDD:293791	5/38 (13%)
		WD40 repeat	349..446	CDD:293791	20/103 (19%)
		WD40 repeat	452..490	CDD:293791	5/45 (11%)
		WD40 repeat	498..524	CDD:293791	11/28 (39%)
CG13074	NP_648835.1	WD40 repeat	189..234	CDD:293791	10/44 (23%)
CG13074	NP_648835.1	WD40 repeat	242..275	CDD:293791	8/46 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1453532at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.110