DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sdic4 and CG13930

DIOPT Version :9

Sequence 1:	NP_001368966.1	Gene:	Sdic4 / 2768886	FlyBaseID:	FBgn0053499	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_647645.1	Gene:	CG13930 / 38210	FlyBaseID:	FBgn0035256	Length:	685	Species:	Drosophila melanogaster

Alignment Length:	384	Identity:	84/384 - (21%)
Similarity:	153/384 - (39%)	Gaps:	75/384 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 GSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWD 275
            |.|.:.:.|.....|.|.|||.| ....||..:|.|..|::..|:...|.|:..|.::|.:.:.|
  Fly   313 GVYSHGKVSKLPRSGWVYVWNIK-NPVNPERRYHYQVPVVTVEFSPTQPQLLAIGLHNGGVEVRD 376

  Fly   276 NRVQKRTPIQRTPLSAAAHTHPVYCLQM------VGTQNAH--NVISISSDGKLCSWSL----DM 328
            ...|...|:..:...::.:..||..::.      ||.:|.|  ..::.|..|.:..:.|    :|
  Fly   377 ISGQDLPPLAVSQRLSSPYFEPVTAIKWIYFEGDVGCRNPHITPFLATSQAGAVTKYRLINSPNM 441

  Fly   329 LSQPQDTL-----ELQ----QRQSKAIAITSMAFPANEINSLVMG----------SEDGYVYSAS 374
            |...|..|     ||:    :||..|.::.:...|  :...:|:.          :::|.:|..|
  Fly   442 LGLEQQRLQRAEGELEGIPIERQPPAASLLANRHP--QCLEIVLDPVQSDIYYVLTDEGTLYKCS 504

  Fly   375 -----RHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFLTSS----IKIW--SLKLPISSC 428
                 :|      .|:.:.|.||...:     :.||....::||..    |:||  .:.|||.:.
  Fly   505 TNYPLQH------LELRQVHDGPAACM-----EFSPWSPRMYLTCGSDWCIRIWLAGILLPIVTL 558

  Fly   429 QFSVVSGINSNKPLYSFEDNSDYMMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVA 493
            |..:       .|::.          ..||..|..:..::..| .:|:|:|...|..|.:|.|:.
  Fly   559 QHHL-------SPVHC----------ARWSRTHSTILVSLSRS-TVDIWDLRNSTMKPVSSTVID 605

  Fly   494 GAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEWSRFNTHLSEIKMNQSD 552
            .........:|..|..:.:|:|||.|.:... |::..|...::.:....:.:....|.|
  Fly   606 ADIFYTTFKFTHCGRSLAVGNEAGNLLMLSF-EDMPFPPHFQYKQLKRAIFKALSMQPD 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sdic4	NP_001368966.1	Dynein_IC2	23..51	CDD:402922
		WD40	196..523	CDD:421866	80/353 (23%)
		WD40 repeat	196..245	CDD:293791	11/33 (33%)
		WD40 repeat	251..289	CDD:293791	8/37 (22%)
		WD40 repeat	298..337	CDD:293791	12/55 (22%)
		WD40 repeat	349..446	CDD:293791	22/117 (19%)
		WD40 repeat	452..490	CDD:293791	9/37 (24%)
		WD40 repeat	498..524	CDD:293791	7/25 (28%)
CG13930	NP_647645.1	WD40	<279..648	CDD:225201	82/367 (22%)
		WD40 repeat	295..344	CDD:293791	11/31 (35%)
		WD40 repeat	350..397	CDD:293791	9/46 (20%)
		WD40 repeat	400..473	CDD:293791	16/72 (22%)
		WD40 repeat	478..513	CDD:293791	5/40 (13%)
		WD40	<518..>593	CDD:295369	22/97 (23%)
		WD40 repeat	524..560	CDD:293791	10/40 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940