DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sdic4 and CG15701

DIOPT Version :9

Sequence 1:	NP_001368966.1	Gene:	Sdic4 / 2768886	FlyBaseID:	FBgn0053499	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_611100.1	Gene:	CG15701 / 36801	FlyBaseID:	FBgn0034095	Length:	1051	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	74/432 - (17%)
Similarity:	137/432 - (31%)	Gaps:	151/432 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 STGGGNGDVLAFDAQG---DDEESSLQNLGNGFTSKLPPGY-----LTHGLPTVKDVAPAITPLE 108
            |.|..|...:|...|.   |.|..:|:.......::.||.|     |:..:....|...:..|.:
  Fly   415 SYGKLNASQVATQTQSPHMDGECQTLEVHSRSSWTQHPPHYGGQFVLSCSVDAELDETWSKQPAD 479

  Fly   109 IKKETEVKK--EVNELSEEQKQMIILS--------ENFQRFVVRAGRVIERALS----------- 152
             :.|..:.:  :::.|.:.:.|.:...        |....|:.||||::...|.
  Fly   480 -EYEASISRLEQLHRLEQARSQQLQQKRLAKSTDLERLNSFLHRAGRLMGLVLEGKTTAHGQGNS 543

  Fly   153 -ENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNN 216
             .||.:.|..:..              |.:.|:|                         ||..|.
  Fly   544 PRNVPLQTGLLNA--------------LPVRRIF-------------------------GSAGNG 569

  Fly   217 E------ESPNEPD-------GVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYS 268
            :      |.|.:.:       .::|||:.. ..|.|..:....:.|.....:....::::.|...
  Fly   570 QLVVTVHECPADSNVYKEDFASLLMVWSLA-NPSQPLRLLSTWAEVSRVALSAQAQDIVVAGLRD 633

  Fly   269 GQIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQ 333
            |.:.:||.|                .||. ||.::              ||.|..:     :..|
  Fly   634 GSVAMWDLR----------------ETHS-YCSKL--------------DGHLTHF-----AATQ 662

  Fly   334 DTLELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGIST 398
            ..:.:.::|.|            |:|::.:|:... |.|...|....||        ...:|:.|
  Fly   663 SVVPMPEQQDK------------EVNAMDLGAVVD-VRSFRSHLNAGGV--------AATSGLQT 706

  Fly   399 HYNQLSPDFGHLFLTSSIKIWSLKLPISSCQFSVVSGINSNK 440
            .|.::  .:..|..:..:.:|:|        ....|..|||:
  Fly   707 TYKEV--QYASLNDSGLLTMWTL--------VEGASSTNSNE 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sdic4	NP_001368966.1	Dynein_IC2	23..51	CDD:402922
		WD40	196..523	CDD:421866	44/258 (17%)
		WD40 repeat	196..245	CDD:293791	10/61 (16%)
		WD40 repeat	251..289	CDD:293791	5/37 (14%)
		WD40 repeat	298..337	CDD:293791	6/38 (16%)
		WD40 repeat	349..446	CDD:293791	18/92 (20%)
		WD40 repeat	452..490	CDD:293791
		WD40 repeat	498..524	CDD:293791
CG15701	NP_611100.1	PTZ00108	<23..270	CDD:240271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100