DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sdic4 and dyci-1

DIOPT Version :9

Sequence 1:NP_001368966.1 Gene:Sdic4 / 2768886 FlyBaseID:FBgn0053499 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_001370459.1 Gene:dyci-1 / 177440 WormBaseID:WBGene00015927 Length:643 Species:Caenorhabditis elegans


Alignment Length:557 Identity:209/557 - (37%)
Similarity:323/557 - (57%) Gaps:52/557 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNG-FTSKLPP 87
            ::|...:||......|::.:|:|.|||.......|:......:.|.::..:..:.:| |..:...
 Worm   105 VDLEFSSVQTACTDNKDSAIYSKGTQTDDERISVGEFSLGSQEFDYDDDMIMPMDHGQFRGRAHS 169

  Fly    88 GYLTHGLPTVKDVAPAITPLE------IKKETEVKKE-----VNELSEEQKQMIILSENFQRFVV 141
            ......||..:::|..:...:      .::|||.||.     |..||:|:|..:.|...|.....
 Worm   170 HDQDSPLPYNEEIAKLLGQTKQGDKGLTRQETEEKKTQTVQIVPPLSDEEKYRLTLDPEFLDSFN 234

  Fly   142 RAGRVIERALSENVDIYTDYIGGGDSEE---ANDERSHARLSLNRVFYDERWSKNRCITSMDWST 203
            |:.:||.|||:|.:||..:|.  .|..|   |:|:..|    |.:|:.||.|:..|.:|.|.:|.
 Worm   235 RSCKVISRALNEEIDICINYT--KDPYEKAIASDDLLH----LAQVYQDETWTAKRLVTGMAFSE 293

  Fly   204 HFPELVVGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYS 268
            |:|:|:..|| ...:.||||.||::|||||.|:.|.|.:.:|||.:.|..||:|:.:|:|.|..|
 Worm   294 HYPDLLAVSY-GPCDIPNEPPGVIVVWNTKSKRMTAEFIVYCQSEIQSVAFARFHAHLLLAGCES 357

  Fly   269 GQIVLWDNRV-QKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQP 332
            |||.:||||: .::.||.|:||:..|||:.|.||.:|||:||||.:|:|.||::|||::|.|:||
 Worm   358 GQICVWDNRLTSRKLPINRSPLTTQAHTYTVSCLAVVGTKNAHNFVSLSRDGRICSWNVDNLTQP 422

  Fly   333 QDTLELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGV---NEVYERHLGPIT 394
            .|..||..::.||.:.|.|:||..|:.:.|:|::.|.:.:|||:|....|   :..|:.|.|.:|
 Worm   423 VDGKELMTKEGKAASATRMSFPIGEMQTFVVGTDTGEILAASRNGADPAVIKTDVCYKGHSGTLT 487

  Fly   395 GISTHYNQLSPDFGHLFLTSS----IKIWSLKLPISSCQFSVVSGINSNKPLYSFEDNSDYMMDV 455
            ||..|......||.|||::||    :|:||.|              ::|.. :|||.:.|.::||
 Worm   488 GIEFHRASGVVDFSHLFISSSHDWTVKLWSTK--------------DANLK-FSFESHPDLVLDV 537

  Fly   456 AWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVAGAPA----LNRVSWTPSGLHVCIGDEA 516
            ||||||||:||::|..|.:.:||||:|.|.|.|.: .|||..    :||:.|:|.|.||.:||:.
 Worm   538 AWSPVHPAVFASIDADGNIFVWNLNEDVEGPVARL-RAGAEGESVYMNRLIWSPDGKHVFVGDDE 601

  Fly   517 GKLYVYDVAENLAQPSRDEWSRFNTHLSEIKMNQSDE 553
            |::::|||.|:|.....:||:||...||::|  ||:|
 Worm   602 GRVHMYDVRESLYVLKSEEWNRFARVLSDMK--QSNE 636

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sdic4NP_001368966.1 Dynein_IC2 23..51 CDD:402922 8/26 (31%)
WD40 196..523 CDD:421866 145/338 (43%)
WD40 repeat 196..245 CDD:293791 22/48 (46%)
WD40 repeat 251..289 CDD:293791 18/38 (47%)
WD40 repeat 298..337 CDD:293791 22/38 (58%)
WD40 repeat 349..446 CDD:293791 33/103 (32%)
WD40 repeat 452..490 CDD:293791 22/37 (59%)
WD40 repeat 498..524 CDD:293791 11/25 (44%)
dyci-1NP_001370459.1 WD40 repeat 286..333 CDD:293791 22/47 (47%)
WD40 repeat 339..383 CDD:293791 20/43 (47%)
WD40 382..>611 CDD:421866 103/244 (42%)
WD40 repeat 388..457 CDD:293791 33/68 (49%)
WD40 repeat 487..528 CDD:293791 17/55 (31%)
WD40 repeat 534..573 CDD:293791 22/39 (56%)
WD40 repeat 581..609 CDD:293791 11/27 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160156646
Domainoid 1 1.000 371 1.000 Domainoid score I475
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H37921
Inparanoid 1 1.050 386 1.000 Inparanoid score I1160
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54336
OrthoDB 1 1.010 - - D1453532at2759
OrthoFinder 1 1.000 - - FOG0001314
OrthoInspector 1 1.000 - - otm14603
orthoMCL 1 0.900 - - OOG6_101571
Panther 1 1.100 - - O PTHR12442
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X812
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1413.910

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