DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rai1 and dxo

DIOPT Version :9

Sequence 1:	NP_996492.1	Gene:	Rai1 / 2768882	FlyBaseID:	FBgn0030793	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	XP_021330453.1	Gene:	dxo / 494170	ZFINID:	ZDB-GENE-040718-286	Length:	404	Species:	Danio rerio

Alignment Length:	360	Identity:	100/360 - (27%)
Similarity:	165/360 - (45%)	Gaps:	28/360 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 MYNTPFPSISRPKCIGVCSINASREFVDDASCASYLAGQPWPPLPFDLNGGIEDVIRKPVENGKR 84
            :|...||...:|..:|..|::|.|.|.:|.....|.. :|.....|:|..|......|..:..|.
Zfish    49 LYERHFPLYKQPLEVGCFSLDARRNFFNDHRQLRYYV-EPRRSPDFNLRDGYTSRFIKRDDGVKE 112

  Fly    85 DLEIMLTYIKQHQKELLRQSSSDARNLRLDSDFVTLRGILRQIMCLQYDNR-SFRVKATLLNGNV 148
            .|:.||.:|.:::.::...:||   :..|..||||.||.|.:::...|:.: .:.:.|....|::
Zfish   113 KLDHMLRWILENRHKMQNSNSS---SCALGVDFVTWRGHLTKVLTTPYETQEGWMMAACKFRGSI 174

  Fly   149 YMCKEETPEQQLENANMSRAQRVMCSWGFKFEQYLTSAQAQGKPVTNVPVNEAEEFMGVYRTNLA 213
            |:.:.||.:.:......|..|..|..||:|||||..:..|.|.|.....||..|.|..|.:|.||
Zfish   175 YISEVETEQARENRETRSERQEEMMYWGYKFEQYTCADGADGTPDPGGVVNTNEAFCTVVQTRLA 239

  Fly   214 GILMLYGAELDC-VDSKEPVDFKDCRVLDSLKFVELKTSVFNMNPHQIRTFKSFKSANWWSQSFL 277
            ...:|:..|:|| :...:......|       :||||||.....|.|...|..:|...||:||||
Zfish   240 DHKLLFSGEVDCRLKDPDAPPAPGC-------YVELKTSAEICTPKQRSNFHRYKLLKWWAQSFL 297

  Fly   278 VGITTLYVGLRDTKGMLQRIDEID---VATLARNK--PWSASAMAWYLEQFLRNLKKLLVNINDP 337
            .|:..:..|.||..|::..::...   ::.:.:|:  .|..:....:...||..:|. :|..:||
Zfish   298 PGVPQIIAGFRDHDGIVVSVETFQTSKISQMIKNEYNCWKPTVCMNFCSDFLTFVKS-IVKEDDP 361

  Fly   338 FAVVQVTFL-----NKHASYEVLRGPEHQILPNWY 367
                ::.:|     .:..:|.|.|...|..:|:||
Zfish   362 ----RLVYLFSWDPRRDVTYTVHRDSTHTFIPDWY 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rai1	NP_996492.1	RAI1	224..296	CDD:285815	24/72 (33%)
dxo	XP_021330453.1	RAI1	249..316	CDD:312244	24/73 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I8106
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38061
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5145
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1034620at2759
OrthoFinder	1	1.000	-	-		FOG0004964
OrthoInspector	1	1.000	-	-		oto41516
orthoMCL	1	0.900	-	-		OOG6_104243
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R331
SonicParanoid	1	1.000	-	-		X3502
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.900