DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33502 and NFU1

DIOPT Version :9

Sequence 1:	NP_996529.1	Gene:	CG33502 / 2768875	FlyBaseID:	FBgn0053502	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001002755.1	Gene:	NFU1 / 27247	HGNCID:	16287	Length:	254	Species:	Homo sapiens

Alignment Length:	190	Identity:	124/190 - (65%)
Similarity:	155/190 - (81%)	Gaps:	3/190 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 RSMFIQTQDTPNPESLKFLPGVDVLGKGNTYDFPNGTTAHNSPLAKLLFRVEGVKGVFFGADFVT 129
            |.|||||||||||.||||:||..|| :..|.|||....|..||||:.|||:||||.||||.||:|
Human    57 RYMFIQTQDTPNPNSLKFIPGKPVL-ETRTMDFPTPAAAFRSPLARQLFRIEGVKSVFFGPDFIT 120

  Fly   130 ISKQ-EGAEWSLIKPEVFAVIMDFFASGLPVLNDAQPNADTEILEDDDETVMMIKELLDTRIRPT 193
            ::|: |..:|:|:||:::|.||||||||||::.:..|:.:.. .|:|||.|.|||||||||||||
Human   121 VTKENEELDWNLLKPDIYATIMDFFASGLPLVTEETPSGEAG-SEEDDEVVAMIKELLDTRIRPT 184

  Fly   194 VQEDGGDIVFMGYEGGVVKLKMQGSCSSCPSSIVTLKNGVQNMLQFYIPEVESVEQVFDE 253
            |||||||:::.|:|.|:|:||:||||:||||||:|||||:||||||||||||.||||.|:
Human   185 VQEDGGDVIYKGFEDGIVQLKLQGSCTSCPSSIITLKNGIQNMLQFYIPEVEGVEQVMDD 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33502	NP_996529.1	Nfu_N	69..149	CDD:285874	47/80 (59%)
CG33502	NP_996529.1	NifU	182..248	CDD:279451	52/65 (80%)
NFU1	NP_001002755.1	Nfu_N	61..148	CDD:214919	53/87 (61%)
		NifU	173..241		54/67 (81%)
		NifU	173..239	CDD:279451	52/65 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160455
Domainoid	1	1.000	122	1.000	Domainoid score	I5677
eggNOG	1	0.900	-	-		E1_COG0694
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6369
Inparanoid	1	1.050	258	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63177
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002982
OrthoInspector	1	1.000	-	-		oto91738
orthoMCL	1	0.900	-	-		OOG6_101229
Panther	1	1.100	-	-	LDO	PTHR11178
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3877
SonicParanoid	1	1.000	-	-		X2337
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790