DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AlkB and alkbh5

DIOPT Version :9

Sequence 1:	NP_001334682.1	Gene:	AlkB / 2768870	FlyBaseID:	FBgn0065035	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001070855.1	Gene:	alkbh5 / 570158	ZFINID:	ZDB-GENE-061013-602	Length:	352	Species:	Danio rerio

Alignment Length:	197	Identity:	49/197 - (24%)
Similarity:	68/197 - (34%)	Gaps:	76/197 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 PE----AAIVNYYPVGSTLSGHTD----HSEPNKSAPLFSFS---FGQTAIFLIGGRSLEEKPTA 240
            ||    :|::|.|..|..:..|.|    ...|..|...||.|   ||  ..||.....:.|....
Zfish   151 PEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFG--CKFLFKPIRVSEPVLH 213

  Fly   241 IYLQSGDVMIMSG----------------ESRLCYHAVPRIIKTQASA------TLSLII----- 278
            :.::.|.|.::||                |.|    ||..:.||:|.|      :||..|
Zfish   214 LPVRRGSVTVLSGYAADDITHCIRPQDIKERR----AVIILRKTRADAPRLDSNSLSPSIVSPKR 274

  Fly   279 ------------EDVDNADIKTRTI--DKDL----------FHDVGNPQ-FW------EPFSRYM 312
                        .|.|.|. :.|.:  ||:|          .||.|:.: .|      ||.:||.
Zfish   275 RHILKAKRSHRKADPDAAH-RPRVLEMDKELQRRSLSSRQRRHDDGSSENSWRRADDREPAARYT 338

  Fly   313 DD 314
            .|
Zfish   339 HD 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AlkB	NP_001334682.1	None
alkbh5	NP_001070855.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..47
		2OG-FeII_Oxy	<104..238	CDD:304390	22/88 (25%)
		Alpha-ketoglutarate binding. /evidence=ECO:0000269\|PubMed:24561204	161..163		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..352		19/82 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3145
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900