DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AlkB and alkbh8

DIOPT Version :9

Sequence 1:	NP_001334682.1	Gene:	AlkB / 2768870	FlyBaseID:	FBgn0065035	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	XP_012812512.2	Gene:	alkbh8 / 550051	XenbaseID:	XB-GENE-985927	Length:	638	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	52/216 - (24%)
Similarity:	82/216 - (37%)	Gaps:	52/216 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 PGIIVIRNPFSERGRRYWSARCLRDFPRTPNIVNLNERLFDESVRSDWWKQLNLCSDGVEFQRIK 138
            ||:|::                 .||. :|.    .||...||:  ||..:.: ....::.:|:|
Frog   146 PGLIIV-----------------EDFV-SPE----QERTMLESI--DWDSETS-SQKSLKHRRVK 185

  Fly   139 SAMRWTTFGYHHNWDTKIYDEEMQSPFPEDLSSLCGLFAQAL------GYADFKPEAAIVNYYPV 197
            .      :||...:|....|::  .|.|..|...|   .:||      |.....|:...:|.|..
Frog   186 H------YGYEFRYDNNNVDKD--KPLPGGLPDFC---TEALRKCVQIGLIKHDPDQLTINQYEP 239

  Fly   198 GSTLSGHTD-HSEPNKSAPLFSFSFGQTAIFLIGGRSLEEKPTAIYLQSGDVMIMSGESR-LCYH 260
            |..:..|.| ||.....  :.|.|.|  |..::..:........:.|....::||||||| |..|
Frog   240 GQGIPPHVDTHSAFEDE--ILSLSLG--AEIVMDFKHPNGSVVPVMLPQRSLLIMSGESRYLWTH 300

  Fly   261 AV-PR---IIKTQASATLSLI 277
            .: ||   :|:.....|:..|
Frog   301 GITPRKFDVIQVSEGQTVGTI 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AlkB	NP_001334682.1	None
alkbh8	XP_012812512.2	RRM_ALKBH8	52..130	CDD:409865
		2OG-FeII_Oxy	147..342	CDD:419693	51/215 (24%)
		Methyltransf_25	419..506	CDD:404528
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910