DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AlkB and SPBC13G1.04c

DIOPT Version :9

Sequence 1:	NP_001334682.1	Gene:	AlkB / 2768870	FlyBaseID:	FBgn0065035	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_596553.3	Gene:	SPBC13G1.04c / 2539935	PomBaseID:	SPBC13G1.04c	Length:	302	Species:	Schizosaccharomyces pombe

Alignment Length:	345	Identity:	99/345 - (28%)
Similarity:	158/345 - (45%)	Gaps:	78/345 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFKLVFKQYKCKS-TSPDLTEVVKIDDCVVKGNDQEKSDNNIVQRLSISNVESLQTMPGVKSPKD 64
            :|:|..|:|||:: |.||::||:               |.|..|......:..::.
pombe    11 VFRLEEKRYKCRADTIPDMSEVL---------------DPNDPQSFGFEALVEIKP--------- 51

  Fly    65 WRTYTLTNHPGIIVIRN-PFSERGRRYWSARCLRDFPRTPNIVNLNE----RLFDESVRSDWWKQ 124
             |.::....||:::::| ..||...:...:..........|..||:.    .|.::|:   |.:.
pombe    52 -RVFSFQKAPGLLILKNYVSSELQMQLLKSIMFTQIQDPENKTNLSPFYQLPLGNDSI---WRRY 112

  Fly   125 LNLCSDGVEF-------------QRIKSAMRWTTFGYHHNWDTKIYDEEMQSP-FPEDLSSLC-G 174
            .|  .||...             :.:...:||.|.|..::|.||.|.:..:|| ||:||.... .
pombe   113 YN--GDGESIIDGLGETKPLTVDRLVHKKLRWVTLGEQYDWTTKEYPDPSKSPGFPKDLGDFVEK 175

  Fly   175 LFAQALGYADFKPEAAIVNYYPVGSTLSGHTDHSEPNKSAPLFSFSFGQTAIFLIGGRSLEEKPT 239
            :..::..:..:|.||||||:|..|.|||.|.|.||.:.:.||.|.|.|...|:|||..|..|||:
pombe   176 VVKESTDFLHWKAEAAIVNFYSPGDTLSAHIDESEEDLTLPLISLSMGLDCIYLIGTESRSEKPS 240

  Fly   240 AIYLQSGDVMIMSGESRLCYHAVPRIIKTQASATLSLIIEDVDNADIKTRTIDKDLFHDVGNPQF 304
            |:.|.||||:||:|.||..:||||:||   .::|.:.::                    .|| :.
pombe   241 ALRLHSGDVVIMTGTSRKAFHAVPKII---PNSTPNYLL--------------------TGN-KA 281

  Fly   305 WEPFSRYMDDSRININIRQV 324
            |:   .::...|:|.|:|||
pombe   282 WD---GWISRKRVNFNVRQV 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AlkB	NP_001334682.1	None
SPBC13G1.04c	NP_596553.3	2OG-FeII_Oxy	65..263	CDD:304390	67/202 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1510
eggNOG	1	0.900	-	-		E1_COG3145
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I1504
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004904
OrthoInspector	1	1.000	-	-		oto100419
orthoMCL	1	0.900	-	-		OOG6_102830
Panther	1	1.100	-	-	LDO	PTHR16557
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R47
SonicParanoid	1	1.000	-	-		X2064
TreeFam	1	0.960	-	-
	12	11.850