DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AlkB and Alkbh2

DIOPT Version :9

Sequence 1:	NP_001334682.1	Gene:	AlkB / 2768870	FlyBaseID:	FBgn0065035	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001346869.1	Gene:	Alkbh2 / 231642	MGIID:	2141032	Length:	239	Species:	Mus musculus

Alignment Length:	120	Identity:	26/120 - (21%)
Similarity:	49/120 - (40%)	Gaps:	20/120 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 LCGLFAQALGYADFKPEAAIVNYYPVGSTLSG--HTDHSEPNKSAPLFSFSFGQTAIFLIGGR-S 233
            :|.:..|...:       .:||.|..|....|  ..|..|....:|:.|.|||....|:...: |
Mouse   123 VCEVTGQTFNF-------VLVNRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFIFRHKDS 180

  Fly   234 LEEKP------TAIYLQSGDVMIMSGESRL-CYHAVP---RIIKTQASATLSLII 278
            ..::|      ..:.|..|.:::|:..:.. .||::|   |::..:.:.|...|:
Mouse   181 RGKRPRRTVEVVRLQLAHGSLLMMNPPTNTHWYHSLPIRKRVLAPRVNLTFRKIL 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AlkB	NP_001334682.1	None
Alkbh2	NP_001346869.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	11..32
		2OG-FeII_Oxy_2	50..232	CDD:372627	25/115 (22%)
		Substrate binding. /evidence=ECO:0000250	80..82
		Substrate binding. /evidence=ECO:0000250	100..102
		Alpha-ketoglutarate binding. /evidence=ECO:0000250	137..139		1/1 (100%)
		Alpha-ketoglutarate binding. /evidence=ECO:0000250	226..232		1/5 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3145
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900