DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr7 and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001096850.2	Gene:	dpr7 / 2768865	FlyBaseID:	FBgn0053481	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	222	Identity:	51/222 - (22%)
Similarity:	84/222 - (37%)	Gaps:	55/222 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LERPFFDDISPRNVSAVVDEIAILRCRVK-NKGNRTVSWMRKRDLHILTTNIYTYTGD--QRFSV 109
            ::.|.|....|.|::..:.:.|...|:.: ..||.|.:|..:.|      |:: :..|  :|.|:
Zfish   223 VQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEED------NVF-FKNDLKRRVSI 280

  Fly   110 IHPPGSEDWDLKIDYAQPRDSGVYECQVNTEPKINLAICLQVIADNDFQDLKTKKRFYDTKSARA 174
            :     .|..|.|...:|.|:|.|.|    .|..:|.......|             |.|....|
Zfish   281 L-----IDGSLIISQVKPEDAGKYTC----SPSNSLGRPPSASA-------------YLTVHYPA 323

  Fly   175 KILGSTE-IHVKRDSTIALACSVNIHAP--SVIWYHGSSVVDFDSLRGGISLETEK------TDV 230
            :::.... |:|.......:.|.|:.:.|  ||.|           .:.|:.|..||      .:.
Zfish   324 RVINMPPVIYVAIGLPGYIRCPVDANPPVTSVKW-----------KKDGLPLRIEKYPGWSQMED 377

  Fly   231 GTTSRLMLTRASLRDSGNYTCVPNGAI 257
            |:.....:|..||   |.|||||..::
Zfish   378 GSIRVSEVTEDSL---GTYTCVPYNSL 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr7	NP_001096850.2	V-set	56..145	CDD:284989	22/91 (24%)
		IG_like	58..140	CDD:214653	21/84 (25%)
		IG_like	179..265	CDD:214653	22/88 (25%)
		Ig	187..257	CDD:299845	20/77 (26%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653
		Ig	41..113	CDD:143165
		IG_like	144..223	CDD:214653	51/222 (23%)
		IGc2	151..208	CDD:197706
		I-set	227..319	CDD:254352	26/120 (22%)
		Ig	<263..319	CDD:299845	17/84 (20%)
		Ig_2	326..414	CDD:290606	22/90 (24%)
		IG_like	329..403	CDD:214653	22/87 (25%)
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910