DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr7 and SDK2

DIOPT Version :9

Sequence 1:NP_001096850.2 Gene:dpr7 / 2768865 FlyBaseID:FBgn0053481 Length:312 Species:Drosophila melanogaster
Sequence 2:NP_001138424.1 Gene:SDK2 / 54549 HGNCID:19308 Length:2172 Species:Homo sapiens


Alignment Length:216 Identity:45/216 - (20%)
Similarity:87/216 - (40%) Gaps:40/216 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 SYLSLNDLTNLERPFFDDISPRNVSAVVDEIAILRCRVKNKGNRTVSWMRKRDLHILTTNIYTYT 102
            :|||:     ||.|.|.....|:::|.::::..:.|:.|.....:::|.  :|..::.....|  
Human   300 AYLSV-----LEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY--KDAAVVEVEKLT-- 355

  Fly   103 GDQRFSVIHPPGSEDWDLKIDYAQPRDSGVYECQVNTEPKINLAICLQVIADNDFQDLKTKKRFY 167
               ||.     ...|..|:|....|.|:|:::|                .|.|...:::|.....
Human   356 ---RFR-----QRNDGGLQISGLVPDDTGMFQC----------------FARNAAGEVQTSTYLA 396

  Fly   168 DTKSARAKILGSTEIHVKRDSTIALACSVN-IHAPSVIWYHGSSVVDFDSLRGGISLETEKTDVG 231
            .|..|.....|..:..|....::.|||..: ...|::.|..|..:     |..| |::..:....
Human   397 VTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERI-----LASG-SVQLPRFTPL 455

  Fly   232 TTSRLMLTRASLRDSGNYTCV 252
            .:..|:::...:.|:|.|||:
Human   456 ESGSLLISPTHISDAGTYTCL 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr7NP_001096850.2 V-set 56..145 CDD:284989 16/88 (18%)
IG_like 58..140 CDD:214653 16/81 (20%)
IG_like 179..265 CDD:214653 16/75 (21%)
Ig 187..257 CDD:299845 15/67 (22%)
SDK2NP_001138424.1 Ig 27..109 CDD:299845
IG_like 40..109 CDD:214653
I-set 120..203 CDD:254352
Ig 132..210 CDD:299845
IG_like 222..304 CDD:214653 2/3 (67%)
IGc2 233..286 CDD:197706
I-set 308..397 CDD:254352 21/116 (18%)
Ig 326..394 CDD:143165 17/95 (18%)
I-set 402..492 CDD:254352 17/81 (21%)
Ig 416..492 CDD:299845 15/67 (22%)
Ig 502..586 CDD:299845
IG_like 502..586 CDD:214653
FN3 590..681 CDD:238020
FN3 693..786 CDD:238020
FN3 794..890 CDD:238020
FN3 895..983 CDD:238020
FN3 993..1087 CDD:238020
FN3 1099..1194 CDD:238020
FN3 1201..1290 CDD:238020
FN3 1301..1394 CDD:238020
FN3 1400..1484 CDD:238020
FN3 1503..1616 CDD:238020
FN3 1626..1719 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1707..1729
FN3 1724..1805 CDD:238020
FN3 1837..1916 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2039..2067
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2098..2172
PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 2166..2172
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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