Protein Alignment dpr7 and OPCML

DIOPT Version :10

• Sequence 1: NP_001096850.2
• Gene: dpr7 / 2768865
• FlyBaseID: FBgn0053481
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_001306032.1
• Gene: OPCML / 4978
• HGNCID: 8143
• Length: 354
• Species: Homo sapiens
• Alignment Length: 354
• Identity: 68/354 - (19%)
• Similarity: 117/354 - (33%)
• Gaps: 147/354 - (41%)

  Fly    60 NVSAVVDEIAILRCRVKNKGNRTVSWMRKRDLHILTTNIYTYTGDQRFSV-------IHPPGSED 117
            ||:....|.|.|||.:.::..| |:|:.:..:        .|.|:.::|:       ::.|  ..
Human    44 NVTVRQGESATLRCTIDDRVTR-VAWLNRSTI--------LYAGNDKWSIDPRVIILVNTP--TQ 97

  Fly   118 WDLKIDYAQPRDSGVYECQVNTE--PKIN-LAICLQVIADNDFQDLKTKKRFYDTKSARAKILG- 178
            :.:.|......|.|.|.|.|.|:  ||.: :.:.:||                     ..:|:.
Human    98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV---------------------PPQIMNI 141

  Fly   179 STEIHVKRDSTIALAC-SVNIHAPSVIWYH-----GSSVVDFDSL-------------------- 217
            |::|.|...|::.|.| ::....|:|.|.|     |...|..|..
Human   142 SSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN 206

  Fly   218 --------------------------------RGGISLET------------EKT---------- 228
                                            :|.:|.|.            |:|
Human   207 DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 271

  Fly   229 --DVGTTSRLMLTRASLRDSGNYTCVPN---GAIPASVRVHVLTGEQ----PAAM--QTSSAIRI 282
              :.|..|.|.....|.:|.||||||..   |...||:.::.::...    |.|:  ..:||.|.
Human   272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEISPSSAVAGPGAVIDGVNSASRA 336

  Fly   283 RAFTAMITIISTKVLLYIS-SLMEHMYLR 310
            .|            .|::| :|:.|.:::
Human   337 LA------------CLWLSGTLLAHFFIK 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr7	NP_001096850.2	V-set	56..145	CDD:462230	23/94 (24%)
		Ig	184..267	CDD:472250	30/167 (18%)
		Ig strand B	190..194	CDD:409353	1/3 (33%)
		Ig strand C	202..206	CDD:409353	1/3 (33%)
		Ig strand E	234..238	CDD:409353	2/3 (67%)
		Ig strand G	261..264	CDD:409353	0/2 (0%)
OPCML	NP_001306032.1	Ig	44..132	CDD:472250	23/98 (23%)
		Ig strand B	53..57	CDD:409353	2/3 (67%)
		Ig strand C	65..69	CDD:409353	2/4 (50%)
		Ig strand E	98..102	CDD:409353	0/3 (0%)
		Ig strand F	112..117	CDD:409353	2/4 (50%)
		Ig strand G	125..128	CDD:409353	0/2 (0%)
		Ig_3	135..206	CDD:464046	14/70 (20%)
		Ig	224..312	CDD:472250	19/87 (22%)
		Ig strand B	240..244	CDD:409353	1/3 (33%)
		Ig strand C	253..257	CDD:409353	0/3 (0%)
		Ig strand E	279..283	CDD:409353	2/3 (67%)
		Ig strand F	293..298	CDD:409353	4/4 (100%)
		Ig strand G	306..309	CDD:409353	1/2 (50%)