DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr7 and IGLON5

DIOPT Version :9

Sequence 1:NP_001096850.2 Gene:dpr7 / 2768865 FlyBaseID:FBgn0053481 Length:312 Species:Drosophila melanogaster
Sequence 2:NP_001094842.1 Gene:IGLON5 / 402665 HGNCID:34550 Length:336 Species:Homo sapiens


Alignment Length:289 Identity:63/289 - (21%)
Similarity:108/289 - (37%) Gaps:80/289 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LNNSPIKIKPFIILVLNLNIWCQYISATSYLSLNDLTNLERPFFDDI-----SPRNVSAVVDEIA 69
            |.|:|   :.|.||:..:.:..:.:...|:.:.:      :|:...:     .|..:..:...:.
Human    88 LINTP---EEFSILITEVGLGDEGLYTCSFQTRH------QPYTTQVYLIVHVPARIVNISSPVT 143

  Fly    70 I-------LRCRVKNKGNRTVSWMRKRDLHILTTNIYTYTGDQRFSVIHPPGSEDWDLKIDYAQP 127
            :       |.|....:...||:|.:.||         .:|            ||...|:|...|.
Human   144 VNEGGNVNLLCLAVGRPEPTVTWRQLRD---------GFT------------SEGEILEISDIQR 187

  Fly   128 RDSGVYEC----QVNTEPKINLAICLQVIADNDFQDLKTKKRFYDTKSARAKILGSTEIHVKRDS 188
            ..:|.|||    .||:.|...     :|:...::....|     |..|||. .||...:      
Human   188 GQAGEYECVTHNGVNSAPDSR-----RVLVTVNYPPTIT-----DVTSART-ALGRAAL------ 235

  Fly   189 TIALACSVNIHAPSVI-WYHGSSVVDFDSLRGGISLETEKTDVGTTSRLMLTRASLRDSGNYTC- 251
               |.|......|:.. ||....::...:.. |:.::||:    |.|.|:....|.|..||||| 
Human   236 ---LRCEAMAVPPADFQWYKDDRLLSSGTAE-GLKVQTER----TRSMLLFANVSARHYGNYTCR 292

  Fly   252 VPN--GAIPASVRVHVLTGEQPAAMQTSS 278
            ..|  ||..||:|:     .:|.:::.|:
Human   293 AANRLGASSASMRL-----LRPGSLENSA 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr7NP_001096850.2 V-set 56..145 CDD:284989 21/104 (20%)
IG_like 58..140 CDD:214653 20/92 (22%)
IG_like 179..265 CDD:214653 24/89 (27%)
Ig 187..257 CDD:299845 20/73 (27%)
IGLON5NP_001094842.1 Ig 41..129 CDD:416386 8/49 (16%)
Ig strand A' 41..46 CDD:409353
Ig strand B 48..56 CDD:409353
CDR1 56..60 CDD:409353
FR2 61..68 CDD:409353
Ig strand C 61..67 CDD:409353
CDR2 69..79 CDD:409353
Ig strand C' 71..74 CDD:409353
Ig strand C' 76..79 CDD:409353
FR3 80..115 CDD:409353 7/29 (24%)
Ig strand D 84..91 CDD:409353 1/2 (50%)
Ig strand E 94..100 CDD:409353 3/5 (60%)
Ig strand F 107..115 CDD:409353 1/7 (14%)
CDR3 116..120 CDD:409353 0/9 (0%)
Ig strand G 120..129 CDD:409353 1/8 (13%)
FR4 122..129 CDD:409353 0/6 (0%)
Ig_3 134..199 CDD:404760 17/85 (20%)
Ig strand B 148..157 CDD:409353 2/8 (25%)
Ig strand C 162..170 CDD:409353 3/7 (43%)
Ig strand F 191..199 CDD:409353 4/7 (57%)
Ig strand G 202..212 CDD:409353 3/14 (21%)
Ig_3 217..295 CDD:404760 25/97 (26%)
putative Ig strand A 218..224 CDD:409353 2/10 (20%)
Ig strand B 234..238 CDD:409353 1/12 (8%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 4/4 (100%)
Ig strand G 301..304 CDD:409353 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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