DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr7 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_001096850.2	Gene:	dpr7 / 2768865	FlyBaseID:	FBgn0053481	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	59/245 - (24%)
Similarity:	99/245 - (40%)	Gaps:	33/245 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NIWCQYISAT--SYLSLNDLTNLERPFFDDISPRNVSAVVDEIAILRCRVKNKGNRTVSWMRKRD 90
            :.|...:.:.  |..|.::|.|.:..|...|:  |.:..|...|:|.|.|.:..:..|:|:|...
  Fly     7 SFWLLLLQSVCFSQASFSELNNSDPKFSGPIN--NSTVPVGRDALLTCVVHDLVSFKVAWLRVDT 69

  Fly    91 LHILTTNIYTYTGDQRFSVIHPPGSEDWDLKIDYAQPRDSGVYECQVNTEPKINLAICLQVIADN 155
            ..||:...:..|.:.|.|:.|.. ...|.|||...|..|.|.|.||:||:|..:....|.|:...
  Fly    70 QTILSIQNHVITKNHRISISHTE-HRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVVPP 133

  Fly   156 DFQDLKTKKRFYDTKSARAKILGSTEIHVKRDSTIALACS-VNIHAPSVIWYHGSS---VVDFDS 216
            |..|.:|.:          .::.||      ...:.|.|| ..:..|::.|....:   ::..|.
  Fly   134 DIVDYQTSQ----------DVVRST------GQNVTLTCSATGVPMPTITWRREEATPILISDDG 182

  Fly   217 LRGGISLETEKTDVGTTSRLMLTRASLRDSGNYTCVPNGAIPASVRVHVL 266
            .|...|:|.:        .|.|.:......|.|.|:.:..:|.:|...|:
  Fly   183 DREVFSVEGQ--------NLTLWQVQRSHMGAYLCIASNGVPPTVSKRVM 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr7	NP_001096850.2	V-set	56..145	CDD:284989	29/88 (33%)
		IG_like	58..140	CDD:214653	26/81 (32%)
		IG_like	179..265	CDD:214653	18/89 (20%)
		Ig	187..257	CDD:299845	14/73 (19%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	28/86 (33%)
		Ig	39..122	CDD:299845	28/83 (34%)
		Ig	132..213	CDD:299845	19/104 (18%)
		IG_like	141..227	CDD:214653	19/108 (18%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910