DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr7 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_001096850.2	Gene:	dpr7 / 2768865	FlyBaseID:	FBgn0053481	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	358	Identity:	74/358 - (20%)
Similarity:	122/358 - (34%)	Gaps:	126/358 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GKHATFLNNSPIKIKPFIILVLNLNIWC----QYISATSYLSLNDLTNLERPFFDDISPRNVSAV 64
            ||:.||  .:.:...|.|:.|    .|.    |.|:..:.:..::..::..|:.:.||
Zfish    36 GKNVTF--KTTVVSTPDILTV----TWTFNKGQPIAMVTVIPSSNTVSVRPPYVNRIS------- 87

  Fly    65 VDEIAILRCRVKNKGNRTVSWMR-----KRD-----LHILTTNIYTYTGDQRFSVIHPPGSEDWD 119
                    |      |||...::     |.|     |.|:|.|....||.....|:.|.    .|
Zfish    88 --------C------NRTTFQLQLGPLVKEDTGEYILTIVTNNGDLVTGQIDLEVLEPV----TD 134

  Fly   120 LKI--DYAQP---RDSGVYECQ---------------------------VNTEPKINLA------ 146
            :||  :..:|   ..:.|..|.                           |..|.||:..
Zfish   135 VKISSNVLEPVEFNSTVVLTCSAKGSFTYKWINGSVPLVVDGTHMQLNAVGNELKISEVRRTDLQ 199

  Fly   147 ---ICLQVIADNDFQDLKTKKRFYDTKSARAKILGS---TEIHVKRDSTIALACSVNIHAPSVI- 204
               :|   ||:|..:..|:.............||.:   |:.::|:.||:.|.|:.:.:.|:.|
Zfish   200 GPIVC---IAENALESGKSAPFNLTVSYGPENILMNQFPTDTYLKKGSTLTLTCTADSNPPATIQ 261

  Fly   205 WYHGSSVVDFDSLRGGISLETEKTDVGTTSRLMLTRASLRDSGNYTCVPNGAIPASVRVHVLTGE 269
            |           :..|::|.:..  |.:.:...|.....::|||||||...|
Zfish   262 W-----------VFNGVNLPSNA--VSSPANFTLNNLEEKNSGNYTCVAYNA------------- 300

  Fly   270 QPAAMQTSSAIRIRAFTAMITIISTKVLLYISS 302
                 ||...|..|  .|.:|::.:.....|||
Zfish   301 -----QTKRYIASR--VAFVTVVESLSGTNISS 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr7	NP_001096850.2	V-set	56..145	CDD:284989	26/130 (20%)
		IG_like	58..140	CDD:214653	21/123 (17%)
		IG_like	179..265	CDD:214653	21/89 (24%)
		Ig	187..257	CDD:299845	18/70 (26%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845	25/119 (21%)
		IG_like	33..128	CDD:214653	25/118 (21%)
		Ig	130..222	CDD:299845	16/98 (16%)
		IG_like	149..222	CDD:214653	11/75 (15%)
		I-set	233..315	CDD:254352	26/114 (23%)
		Ig_2	235..315	CDD:290606	26/112 (23%)
		IGc2	335..398	CDD:197706
		Ig_2	427..494	CDD:290606
		IG_like	427..479	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910