DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr7 and negr1

DIOPT Version :9

Sequence 1:NP_001096850.2 Gene:dpr7 / 2768865 FlyBaseID:FBgn0053481 Length:312 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:324 Identity:70/324 - (21%)
Similarity:112/324 - (34%) Gaps:107/324 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 SYLSLNDLTNLERPFFDDISPRNVSAVVDEIAILRCRVKNKGNRTVSWMRKRDLHILTTNIYTYT 102
            |.|......:.:.|..|::..|.     .|.|:|||.:: :|....:|:.:..:        .:.
 Frog    31 SCLPAGQSMDFQWPAVDNLVVRQ-----GETAMLRCFLE-EGASKGAWLNRSSI--------IFA 81

  Fly   103 GDQRFSV-----IHPPGSEDWDLKIDYAQPRDSGVYECQVNTE---------------PKI---- 143
            |..::||     |.....:::.|:|......|.|.|.|.|.||               |||    
 Frog    82 GGDKWSVDPRVSIATSSKQEYSLRIQKVDVSDDGPYTCSVQTEHSPRTLQVHLTVHVSPKIYDIS 146

  Fly   144 ---------NLA-ICL----------------------------------------QVIADND-- 156
                     |:: |||                                        :..|:||  
 Frog   147 SDMTVNEGTNVSLICLATGKPEPSISWRHISPSAKQFGSGQYLDIYGITRDQAGDYECSAENDVS 211

  Fly   157 FQDLKTKKRFYDTKSARAKILGSTEIHVKRDSTIALAC-SVNIHAPSVIWYHGSSVVDFDSLRGG 220
            |.|:|..|   .|.:....||..|...|....|..:.| :..:.||...||.|..  ...:.:.|
 Frog   212 FPDVKKVK---VTVNFAPTILEITPTGVSLGRTGLIRCETAAVPAPVFEWYKGEK--KLTNGQRG 271

  Fly   221 ISLETEKTDVGTTSRLMLTRASLRDS--GNYTCV---PNGAIPASVRVHVLTGEQPAAMQTSSA 279
            |.::...|      |.:||.:::.:.  ||||||   ..|...||:.::.:......:..||||
 Frog   272 IRIQNYNT------RSILTVSNVTEEHFGNYTCVAVNKLGTSNASLPLNQIIEPSTTSPVTSSA 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr7NP_001096850.2 V-set 56..145 CDD:284989 24/121 (20%)
IG_like 58..140 CDD:214653 19/86 (22%)
IG_like 179..265 CDD:214653 24/91 (26%)
Ig 187..257 CDD:299845 20/75 (27%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 23/105 (22%)
FR1 44..62 CDD:409353 7/22 (32%)
Ig strand A' 47..53 CDD:409353 1/5 (20%)
Ig strand B 55..63 CDD:409353 5/7 (71%)
CDR1 63..68 CDD:409353 1/5 (20%)
FR2 69..75 CDD:409353 1/5 (20%)
Ig strand C 69..74 CDD:409353 1/4 (25%)
CDR2 76..87 CDD:409353 1/18 (6%)
Ig strand C' 78..82 CDD:409353 0/11 (0%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
FR3 88..122 CDD:409353 8/33 (24%)
Ig strand D 91..98 CDD:409353 1/6 (17%)
Ig strand E 101..107 CDD:409353 1/5 (20%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 2/3 (67%)
Ig strand G 127..136 CDD:409353 0/8 (0%)
FR4 129..136 CDD:409353 0/6 (0%)
Ig_3 140..208 CDD:404760 8/67 (12%)
Ig strand A' 146..151 CDD:409353 0/4 (0%)
Ig strand B 157..164 CDD:409353 3/6 (50%)
Ig strand C 170..175 CDD:409353 0/4 (0%)
Ig strand C' 177..179 CDD:409353 0/1 (0%)
Ig strand E 187..193 CDD:409353 0/5 (0%)
Ig strand F 200..207 CDD:409353 0/6 (0%)
Ig strand G 214..222 CDD:409353 3/10 (30%)
Ig_3 226..302 CDD:404760 23/83 (28%)
putative Ig strand A 226..232 CDD:409353 2/5 (40%)
Ig strand B 242..246 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 281..285 CDD:409353 1/3 (33%)
Ig strand F 295..300 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 46 1.000 Domainoid score I11916
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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