DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33225 and CG30187

DIOPT Version :9

Sequence 1:	NP_001286682.1	Gene:	CG33225 / 2768860	FlyBaseID:	FBgn0053225	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	93/269 - (34%)
Similarity:	146/269 - (54%)	Gaps:	20/269 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LGSSTLLTNDCGTTRHPSRIRRVVGGNDADRFANPWMVMVLGENNVFCSGSLITRLFVLTSASCL 99
            :|:|..|...||.    :...::.||::|....:.||..|....:..|.|:||.:.||||:|.|:
  Fly    18 VGASIFLDQICGI----NIALKITGGHNAAFQNSVWMAAVHNRTHFICGGTLIHKRFVLTAAHCI 78

  Fly   100 LSLPKQ-VILGEYDRNCTSADCTSIRQVIDIDQKIIHGQFGLETVKKYDIALLRLAKKVSISDYV 163
            :....| |.||.|::: ..||    |:  |:...::|..|.:....:.||.||:|:..|..:..:
  Fly    79 VDQDVQSVSLGAYNKS-DPAD----RK--DVITAVVHSSFDVRASYENDIGLLKLSSDVIFNALI 136

  Fly   164 RPICLSVDRQVG---RSVQHFTATGWGTTEWNEPSTILQTVTLSKINRKYCKGRLRQNIDASQLC 225
            ||||:.:::.:.   |:::.|.|.||||...|:.|.||||:.|:.::|:.|...|.......|:|
  Fly   137 RPICIVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQTIILNHLDREECYMELSVYPSEKQIC 201

  Fly   226 VGGPRKDTCSGDAGGPLSLTLKIDGDGKWNNKSRAFLIGIVSYGSSSCSGIGVYTNVEHYMDWIV 290
            .|.|..|||.||:||||:..:.|.|.|     :|....||:|.|.:||.|.||||::..:.|||.
  Fly   202 AGVPSGDTCGGDSGGPLTNDVFIQGIG-----NREVQFGIISVGKTSCDGQGVYTDLMSFADWIK 261

  Fly   291 RTINKSNTE 299
            .||.:.:.|
  Fly   262 MTIERLSIE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	83/236 (35%)
CG33225	NP_001286682.1	Tryp_SPc	57..292	CDD:238113	85/238 (36%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	83/236 (35%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860