DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33225 and CLIPB4

DIOPT Version :9

Sequence 1:	NP_001286682.1	Gene:	CG33225 / 2768860	FlyBaseID:	FBgn0053225	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_307755.1	Gene:	CLIPB4 / 1269159	VectorBaseID:	AGAP003250	Length:	360	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	100/291 - (34%)
Similarity:	149/291 - (51%)	Gaps:	53/291 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GARLGSSTLL--TNDCGTTRHPSRIRRVVGGNDA--DRFANPWMVMVLGE--NNVF---CSGSLI 87
            |.|....|.|  :.:||.    ....||:||...  |.|  ||..::..|  |..|   |.||:|
Mosquito    85 GVRSKGKTSLPESPNCGV----QLTDRVIGGQPTKIDEF--PWTALIEYEKPNGRFGFHCGGSVI 143

  Fly    88 TRLFVLTSASCLLSLPK-----QVILGEYDRNCTS-------ADCTSIRQVIDIDQKIIHGQFGL 140
            ...::||:|.|:.|:|:     :|.|||:|.:.|:       ||...   .:||::.|:|..:.|
Mosquito   144 NERYILTAAHCITSIPRGWKVHRVRLGEWDLSSTTDQEDDFYADAPI---DLDIEKIIVHPGYNL 205

  Fly   141 ETVKKY-DIALLRLAKKVSISDYVRPICLSVDRQVGRSVQH----FTATGWGTTEWNEPSTILQT 200
            :....: ||||:|..::::.|..:..|||.:...: |:.:|    ..|.|||.||....|.....
Mosquito   206 QDKSHHNDIALIRFNREINYSSTISAICLPLSNSL-RNRKHAGLSSYAAGWGKTETASASQKKLK 269

  Fly   201 VTLSKINRKYCKGRLRQN---IDASQLCVGGPR-KDTCSGDAGGPLSLTLKIDGDGKWNNKSRAF 261
            |.|:.::.|.|....::|   :|::|:|.||.| |||||||:||||...:    .|.|      :
Mosquito   270 VELTVVDVKDCSPAYQRNGISLDSTQMCAGGIRGKDTCSGDSGGPLMRQM----SGSW------Y 324

  Fly   262 LIGIVSYGSSSCS--GI-GVYTNVEHYMDWI 289
            |||:||:|...|.  |: ||||||..|:|||
Mosquito   325 LIGVVSFGPQKCGAPGVPGVYTNVAEYVDWI 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	92/263 (35%)
CG33225	NP_001286682.1	Tryp_SPc	57..292	CDD:238113	93/264 (35%)
CLIPB4	XP_307755.1	CLIP	31..83	CDD:371857
CLIPB4	XP_307755.1	Tryp_SPc	108..358	CDD:238113	93/264 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910