DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33225 and mst1

DIOPT Version :9

Sequence 1:	NP_001286682.1	Gene:	CG33225 / 2768860	FlyBaseID:	FBgn0053225	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_004915630.2	Gene:	mst1 / 100494056	XenbaseID:	XB-GENE-487985	Length:	736	Species:	Xenopus tropicalis

Alignment Length:	280	Identity:	68/280 - (24%)
Similarity:	111/280 - (39%)	Gaps:	60/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GSSTLLTNDCGTTRHPSRIR-RVVGGNDADRFANPWMVMV---LGENNVFCSGSLITRLFVLTSA 96
            |:..::.:.||.....|..| |:|||...:   :||.|.:   .||:  ||.|||:...:|:::.
Frog   484 GAENIVFDSCGKRNDRSSQRTRIVGGMPGN---SPWTVSLRNRQGEH--FCGGSLVKENWVISTR 543

  Fly    97 SCLLSLPK-----QVILGEYDRNCTSADCTSIRQVIDIDQKIIHGQFGLETVKKYDIALLRLAKK 156
            .|..|...     |.::|...:|.:..|  ..||.:.| .||:.|.      ....:.:|:|.:.
Frog   544 QCFSSCDADLSGYQAVMGTLFKNPSPDD--PDRQSVPI-SKIVCGP------SDSSLVMLKLERP 599

  Fly   157 VSISDYVRPICLSVDRQVGRSVQHFTATGWGTTEWNEPSTILQTVTLSKINRKYCKGRLRQN--- 218
            |:::..|..|||..:|.:..........|||.|.......:|:......|:...|....|..
Frog   600 VTLNSRVALICLPPERYIVPEATKCEIAGWGDTGGTGHDNVLKIAIFHIISNDECNKNYRSQRNK 664

  Fly   219 -IDASQLCVGGPRKD--TCSGDAGGPLS-----------LTLKIDGDGKWNNKSRAFLIGIVSYG 269
             :| :::|......|  .|.||.||||:           :.:...|.||.|..:
Frog   665 VLD-NEMCTKPVPVDVGACEGDYGGPLACLTHDCWVLEGVIVPARGCGKKNQPA----------- 717

  Fly   270 SSSCSGIGVYTNVEHYMDWI 289
                    ::|.|..|:|||
Frog   718 --------IFTRVSVYVDWI 729

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	61/257 (24%)
CG33225	NP_001286682.1	Tryp_SPc	57..292	CDD:238113	62/258 (24%)
mst1	XP_004915630.2	PAN_AP_HGF	36..114	CDD:238532
		KR	118..198	CDD:214527
		KR	201..279	CDD:214527
		KR	308..390	CDD:214527
		KR	397..474	CDD:412161
		Tryp_SPc	506..732	CDD:238113	62/258 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910