DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33226 and MASP1

DIOPT Version :9

Sequence 1:NP_995917.3 Gene:CG33226 / 2768859 FlyBaseID:FBgn0069056 Length:292 Species:Drosophila melanogaster
Sequence 2:XP_011511291.1 Gene:MASP1 / 5648 HGNCID:6901 Length:735 Species:Homo sapiens


Alignment Length:306 Identity:80/306 - (26%)
Similarity:133/306 - (43%) Gaps:69/306 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 LGQDLLDPNCV-------QTPVGVREQILGGHNADIKLHPWMVQI-------LQRGYHFCGGSLI 77
            ||:.|  |.|:       ::...:.::|:||.||:..|.||...|       :.....|..|:|:
Human   432 LGRSL--PTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALL 494

  Fly    78 SSLFVLTAAHCHSRYRLKVRFGRYSGITPRYLCSSQYCSPFGPEIDVK-----------RIFLHS 131
            |:.::|||||.....|      |.:.:.|   .|.::.:.:....||:           |:.||.
Human   495 SASWILTAAHVLRSQR------RDTTVIP---VSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHP 550

  Fly   132 SYR-DYHNYDIALFLLAKPVRYNVQTRPICVLQTSNKDKLRQFLNYVAMFNVTGWGKTESQLT-- 193
            .:. ..:|:||||..|.:||.......|:|:.:...:......|..||     |||.:...:|  
Human   551 DFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVA-----GWGISNPNVTVD 610

  Fly   194 ----------STILQTTSLFHLDRKFCAQIFDRKIGWPHI-----CAGHSQ--SSTCTGDSGGPL 241
                      |.:||...|..:....|...::.:.|...:     |||:.:  ..||.|||||  
Human   611 EIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGG-- 673

  Fly   242 SAELTFSGV-KRTVLFGIISYGAP-NC--REV-TVFTNVLRYSNWI 282
             |.:.|..: :|.|:.|::|:|.| .|  ::| .|:|.|..|.:|:
Human   674 -AFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV 718

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33226NP_995917.3 Tryp_SPc 47..285 CDD:238113 75/279 (27%)
Tryp_SPc 47..282 CDD:214473 74/277 (27%)
MASP1XP_011511291.1 CUB 35..144 CDD:238001
FXa_inhibition 160..188 CDD:291342
CUB 192..301 CDD:278839
Sushi 308..369 CDD:278512
CCP 374..439 CDD:153056 4/8 (50%)
Tryp_SPc 456..718 CDD:214473 74/278 (27%)
Tryp_SPc 457..718 CDD:238113 74/277 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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