DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33226 and hgfa

DIOPT Version :9

Sequence 1:	NP_995917.3	Gene:	CG33226 / 2768859	FlyBaseID:	FBgn0069056	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	XP_005164799.1	Gene:	hgfa / 493781	ZFINID:	ZDB-GENE-041014-2	Length:	712	Species:	Danio rerio

Alignment Length:	281	Identity:	68/281 - (24%)
Similarity:	97/281 - (34%)	Gaps:	75/281 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PNCVQTPVGVREQILGGHNAD-IKLHPWMVQILQRGYHFCGGSLISSLFVLTAAHCHSRYRLKVR 97
            |:|.   :....:|:||.... .:...|:|.|.:...|:||||||...:|||...|.|.
Zfish   467 PSCF---IHKTTRIVGGMRVQRAEDGSWVVSIQKGNRHWCGGSLIREEWVLTDQQCFST------ 522

  Fly    98 FGRYSGITPRYLCSSQYCSPFGPEIDVKRIFLH-------SSYRDYH------NYDIALFLLAKP 149
                             |.|...|..|:...||       .:.|..|      ..::||..|..|
Zfish   523 -----------------CVPDLSEYTVQVGLLHLNASAGTQALRIAHVVCGPEGSNLALLKLTTP 570

  Fly   150 VRYNVQTRPI------CVLQTSNKDKLRQFLNYVAMFNVTGWGKTESQLTSTILQTTSLFHLDRK 208
            ...:...|.:      |.:...            .:..:.|||.|:.......|:...|..:..|
Zfish   571 APLSEHVRTVQLPVAGCAVAEG------------TLCLMYGWGDTKGTGHEGSLKMVGLPIVSNK 623

  Fly   209 FCAQ-------IFDRKIGWPHICAGHSQ-SSTCTGDSGGPLSAELTFSGVKRTVL-FGIISYGAP 264
            .|:|       |.:.|     ||||..: ...|..|.||||..:   .|..:.:: ..|...|..
Zfish   624 RCSQSHNGILPITETK-----ICAGGKRDQGVCEKDYGGPLVCQ---EGESKVIVGVSINGRGCA 680

  Fly   265 NCREVTVFTNVLRYSNWIRDI 285
            ..|...||.||..||.|||.:
Zfish   681 VARRPAVFVNVAFYSEWIRKV 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33226	NP_995917.3	Tryp_SPc	47..285	CDD:238113	66/266 (25%)
CG33226	NP_995917.3	Tryp_SPc	47..282	CDD:214473	63/263 (24%)
hgfa	XP_005164799.1	PAN_AP_HGF	<50..107	CDD:238532
		KR	111..192	CDD:238056
		KR	195..275	CDD:214527
		KR	287..367	CDD:214527
		KR	374..451	CDD:214527
		Tryp_SPc	476..698	CDD:214473	63/264 (24%)
		Tryp_SPc	477..701	CDD:238113	66/266 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575859
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930