DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33226 and MST1

DIOPT Version :10

Sequence 1:NP_995917.3 Gene:CG33226 / 2768859 FlyBaseID:FBgn0069056 Length:292 Species:Drosophila melanogaster
Sequence 2:NP_001380510.1 Gene:MST1 / 4485 HGNCID:7380 Length:737 Species:Homo sapiens


Alignment Length:286 Identity:67/286 - (23%)
Similarity:98/286 - (34%) Gaps:85/286 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 GQDLLDPNCVQTPVGVREQILGGHNADIKLHPWMVQILQRGYHFCGGSLISSLFVLTAAHCHSRY 92
            ||........|.||..||:                  |::|.|||||||:...::|||..|.|..
Human   507 GQSACGIGEAQLPVSHREE------------------LRQGQHFCGGSLVKEQWILTARQCFSSC 553

  Fly    93 RLKV--------------RFGRYSGITPRYLCSSQYCSPFGPEIDVKRIFLHSSYRDYHNYDIAL 143
            .:.:              :.|..|  ..|...:...|.|.|.:                   :.|
Human   554 HMPLTGYEVWLGTLFQNPQHGEPS--LQRVPVAKMVCGPSGSQ-------------------LVL 597

  Fly   144 FLLAKPVRYNVQTRPIC------VLQTSNKDKLRQFLNYVAMFNVTGWGKTESQLTSTILQTTSL 202
            ..|.:.|..|.:...||      |:....|            ..:.|||:|:.....|:|....|
Human   598 LKLERSVTLNQRVALICLPPEWYVVPPGTK------------CEIAGWGETKGTGNDTVLNVALL 650

  Fly   203 FHLDRKFCAQIFDRKIGWPHICAGH--SQSSTCTGDSGGPLSAELTFSGVKRTVLFGIISYGAPN 265
            ..:..:.|......::....:|...  :....|.||.||||:.   |:. ...||.|||   .||
Human   651 NVISNQECNIKHRGRVRESEMCTEGLLAPVGACEGDYGGPLAC---FTH-NCWVLEGII---IPN 708

  Fly   266 --C---REVTVFTNVLRYSNWIRDIV 286
              |   |...|||.|..:.:||..::
Human   709 RVCARSRWPAVFTRVSVFVDWIHKVM 734

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33226NP_995917.3 Tryp_SPc 47..285 CDD:238113 60/264 (23%)
MST1NP_001380510.1 PAN_AP_HGF 37..118 CDD:238532
KR 122..202 CDD:214527
KR 202..>241 CDD:412161
PHA03247 <234..457 CDD:223021
Tryp_SPc 527..733 CDD:238113 59/245 (24%)
Blue background indicates that the domain is not in the aligned region.

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