Protein Alignment CG33226 and GZMK

DIOPT Version :10

• Sequence 1: NP_995917.3
• Gene: CG33226 / 2768859
• FlyBaseID: FBgn0069056
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 80/287 - (27%)
• Similarity: 118/287 - (41%)
• Gaps: 43/287 - (14%)

  Fly    21 LRSYESLGQDLLDPNCVQTPVGVREQILGGHNADIKLHPWMVQILQRGYHFCGGSLISSLFVLTA 85
            :..:.|.....|......|.|....:|:||........|:|..|...|:|.|||.||...:||||
Human     1 MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTA 65

  Fly    86 AHCHSRYRLKVRFGRYSGITPRYLCSSQYCS---PFGPEIDVKRIFLHSSY-RDYHNYDIALFLL 146
            |||..|:.        .|.:|..:..:...|   .....:::|:....|.. .|..:.||.|..|
Human    66 AHCQYRFT--------KGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKL 122

  Fly   147 AKPVRYNVQTRPICVLQTSNKDKLRQFLNYVAMFNVTGWGKT--ESQLTSTILQTTSLFHLDRKF 209
            ....:.|   :.:.:|...:|..||.    .....|||||.|  :|...|..|:..::..|.||.
Human   123 QTAAKLN---KHVKMLHIRSKTSLRS----GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKL 180

  Fly   210 C-AQIF---DRKIGWPHICAGHS--QSSTCTGDSGGPLSAELTFSGVKRTVLFGIISYGAPNCRE 268
            | :|.:   |..|....:|||.:  |..:|.|||||||        :.:.|...|:| |...|..
Human   181 CNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPL--------ICKGVFHAIVS-GGHECGV 236

  Fly   269 VT---VFTNVL-RYSNWIRDIVHNFTP 291
            .|   ::|.:. :|..||:.   |..|
Human   237 ATKPGIYTLLTKKYQTWIKS---NLVP 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33226	NP_995917.3	Tryp_SPc	47..285	CDD:238113	74/253 (29%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	74/256 (29%)