DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33226 and Habp2

DIOPT Version :9

Sequence 1:	NP_995917.3	Gene:	CG33226 / 2768859	FlyBaseID:	FBgn0069056	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	93/329 - (28%)
Similarity:	143/329 - (43%)	Gaps:	88/329 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KMKW----LLVC--------------FILALRSYESLGQDLLDPNCVQTPVGVREQILGGHNADI 55
            |:||    :.||              .::.|..::|.|:..:..:.|       ::|.||..:..
  Rat   263 KVKWEYCNVEVCPESDAANPLGSLQEPVMELPGFDSCGKTEMTEHAV-------KRIYGGFKSTA 320

  Fly    56 KLHPWMVQI---------LQRGYHFCGGSLISSLFVLTAAHC--HSRYRLKVRFGRYSGITPRYL 109
            ..|||.|.:         :.:| ||||||||...:|||||||  .|...|||..|..
  Rat   321 GKHPWQVSLQTSLPLTTSMPQG-HFCGGSLIHPCWVLTAAHCTDMSTKHLKVVLGDQ-------- 376

  Fly   110 CSSQYCSPFGPEIDVKRIFLHSSYRDY----HNYDIALFLLAKPVRYNVQTRPICVLQTSNKDKL 170
             ..:..........|::|..:|.|.:.    || ||||..| |||..:      |.|::
  Rat   377 -DLKKTESHEQTFRVEKILKYSQYNERDEIPHN-DIALLKL-KPVGGH------CALES------ 426

  Fly   171 RQFLNYVAM----------FNVTGWGKTESQLTSTILQTTSLFHLDRKFC--AQIFDRKIGWPHI 223
             :::..|.:          .:::|||.||:...|..|....:..:....|  .|::|..|....|
  Rat   427 -KYVKTVCLPSDPFPSGTECHISGWGVTETGEGSRQLLDAKVKLIANALCNSRQLYDHTIDDSMI 490

  Fly   224 CAGHSQ---SSTCTGDSGGPLSAEL--TFSGVKRTVLFGIISYGAPNCREVTVFTNVLRYSNWIR 283
            |||:.|   |.||.|||||||:.|.  |:      .::||:|:|....::..|:|.|.::.|||:
  Rat   491 CAGNLQKPGSDTCQGDSGGPLTCEKDGTY------YVYGIVSWGQECGKKPGVYTQVTKFLNWIK 549

  Fly   284 DIVH 287
            ..:|
  Rat   550 TTMH 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33226	NP_995917.3	Tryp_SPc	47..285	CDD:238113	83/269 (31%)
CG33226	NP_995917.3	Tryp_SPc	47..282	CDD:214473	81/266 (30%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056	4/11 (36%)
		Tryp_SPc	312..551	CDD:238113	83/269 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336755
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840