DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33226 and CG30187

DIOPT Version :9

Sequence 1:	NP_995917.3	Gene:	CG33226 / 2768859	FlyBaseID:	FBgn0069056	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	96/284 - (33%)
Similarity:	135/284 - (47%)	Gaps:	29/284 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IEFKMKWLLVCFILALRSYESLGQDL-LDPNCVQTPVGVREQILGGHNADIKLHPWMVQILQRGY 69
            ::.::.|:.|.|..    .:.:|..: ||..|   .:.:..:|.|||||..:...||..:..|.:
  Fly     1 MQTRLAWIPVIFWF----LKDVGASIFLDQIC---GINIALKITGGHNAAFQNSVWMAAVHNRTH 58

  Fly    70 HFCGGSLISSLFVLTAAHCHSRYRLK-VRFGRYSGITPRYLCSSQYCSPFGPEIDVKRIFLHSSY 133
            ..|||:||...||||||||.....:: |..|.|:...|            ....||....:|||:
  Fly    59 FICGGTLIHKRFVLTAAHCIVDQDVQSVSLGAYNKSDP------------ADRKDVITAVVHSSF 111

  Fly   134 ---RDYHNYDIALFLLAKPVRYNVQTRPICVLQTSNKDKLRQFLNYVAMFNVTGWGKTESQLTST 195
               ..|.| ||.|..|:..|.:|...||||::  .||.......| :..|...|||......||.
  Fly   112 DVRASYEN-DIGLLKLSSDVIFNALIRPICIV--LNKSMANHMRN-MRTFKAFGWGTLRGNKTSD 172

  Fly   196 ILQTTSLFHLDRKFCAQIFDRKIGWPHICAGHSQSSTCTGDSGGPLSAELTFSGV-KRTVLFGII 259
            ||||..|.||||:.|............||||.....||.|||||||:.::...|: .|.|.||||
  Fly   173 ILQTIILNHLDREECYMELSVYPSEKQICAGVPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGII 237

  Fly   260 SYGAPNCREVTVFTNVLRYSNWIR 283
            |.|..:|....|:|:::.:::||:
  Fly   238 SVGKTSCDGQGVYTDLMSFADWIK 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33226	NP_995917.3	Tryp_SPc	47..285	CDD:238113	89/242 (37%)
CG33226	NP_995917.3	Tryp_SPc	47..282	CDD:214473	87/239 (36%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	87/240 (36%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860