DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33226 and Habp2

DIOPT Version :9

Sequence 1:	NP_995917.3	Gene:	CG33226 / 2768859	FlyBaseID:	FBgn0069056	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001316864.1	Gene:	Habp2 / 226243	MGIID:	1196378	Length:	554	Species:	Mus musculus

Alignment Length:	329	Identity:	92/329 - (27%)
Similarity:	143/329 - (43%)	Gaps:	88/329 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KMKW----LLVC--------------FILALRSYESLGQDLLDPNCVQTPVGVREQILGGHNADI 55
            |:||    :.||              .::.|..:||.|:..:..:.|       ::|.||..:..
Mouse   259 KVKWEYCDVTVCPVPDTPNPVESLLEPVMELPGFESCGKTEVAEHAV-------KRIYGGFKSTA 316

  Fly    56 KLHPWMVQI---------LQRGYHFCGGSLISSLFVLTAAHCH--SRYRLKVRFGRYSGITPRYL 109
            ..|||.|.:         :.:| |||||:||...:|||||||.  :...|||..|..
Mouse   317 GKHPWQVSLQTSLPLTTSMPQG-HFCGGALIHPCWVLTAAHCTDINTKHLKVVLGDQ-------- 372

  Fly   110 CSSQYCSPFGPEIDVKRIFLHSSYRDY----HNYDIALFLLAKPVRYNVQTRPICVLQTSNKDKL 170
             ..:..........|::|..:|.|.:.    || ||||..| |||..:      |.|::
Mouse   373 -DLKKTESHEQTFRVEKILKYSQYNERDEIPHN-DIALLKL-KPVGGH------CALES------ 422

  Fly   171 RQFLNYVAM----------FNVTGWGKTESQLTSTILQTTSLFHLDRKFC--AQIFDRKIGWPHI 223
             :::..|.:          .:::|||.||:...|..|....:..:....|  .|::|..|....|
Mouse   423 -RYVKTVCLPSDPFPSGTECHISGWGVTETGEGSRQLLDAKVKLIANPLCNSRQLYDHTIDDSMI 486

  Fly   224 CAGHSQ---SSTCTGDSGGPLSAEL--TFSGVKRTVLFGIISYGAPNCREVTVFTNVLRYSNWIR 283
            |||:.|   |.||.|||||||:.|.  |:      .::||:|:|....::..|:|.|.::.|||:
Mouse   487 CAGNLQKPGSDTCQGDSGGPLTCEKDGTY------YVYGIVSWGQECGKKPGVYTQVTKFLNWIK 545

  Fly   284 DIVH 287
            ..:|
Mouse   546 TTMH 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33226	NP_995917.3	Tryp_SPc	47..285	CDD:238113	81/269 (30%)
CG33226	NP_995917.3	Tryp_SPc	47..282	CDD:214473	79/266 (30%)
Habp2	NP_001316864.1	EGF_CA	67..103	CDD:238011
		EGF_CA	150..182	CDD:238011
		KR	187..271	CDD:238056	4/11 (36%)
		Tryp_SPc	308..547	CDD:238113	81/269 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833192
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930