DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33226 and Hgf

DIOPT Version :9

Sequence 1:	NP_995917.3	Gene:	CG33226 / 2768859	FlyBaseID:	FBgn0069056	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	283	Identity:	69/283 - (24%)
Similarity:	100/283 - (35%)	Gaps:	96/283 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 QTPVGVREQILGGHNADIKLHPWMVQILQRGYHFCGGSLISSLFVLTAAHCH-SRYRLKVRFGRY 101
            ||.||                 |||.:..|..|.||||||...:||||..|. :|.:....:..:
Mouse   503 QTTVG-----------------WMVSLKYRNKHICGGSLIKESWVLTARQCFPARNKDLKDYEAW 550

  Fly   102 SGI----------TPRYLCSSQYCSPFGPEIDVKRIFLHSSYRDYHNYDIALFLLAKPVRYNVQT 156
            .||          ..:.|..||..  :|||                ..|:.|..||:|
Mouse   551 LGIHDVHERGEEKRKQILNISQLV--YGPE----------------GSDLVLLKLARP------- 590

  Fly   157 RPICVLQTSNKDKLRQFLNYVAMF---------------NVTGWGKTESQLTSTILQTTSLFHLD 206
               .:|.           |:|:..               ::.|||.|.......:|:...|:.:.
Mouse   591 ---AILD-----------NFVSTIDLPSYGCTIPEKTTCSIYGWGYTGLINADGLLRVAHLYIMG 641

  Fly   207 RKFCAQIFDRKI--GWPHICAGHSQ--SSTCTGDSGGPLSAELTFSGVKRTVLFGIISYG----A 263
            .:.|:|....|:  ....:|||..:  |..|.||.||||..|..    |..::.|:|..|    .
Mouse   642 NEKCSQHHQGKVTLNESELCAGAEKIGSGPCEGDYGGPLICEQH----KMRMVLGVIVPGRGCAI 702

  Fly   264 PNCREVTVFTNVLRYSNWIRDIV 286
            ||  ...:|..|..|:.||..::
Mouse   703 PN--RPGIFVRVAYYAKWIHKVI 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33226	NP_995917.3	Tryp_SPc	47..285	CDD:238113	65/271 (24%)
CG33226	NP_995917.3	Tryp_SPc	47..282	CDD:214473	63/268 (24%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056
		Tryp_SPc	495..719	CDD:214473	67/277 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833150
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930