DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and cxadr

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_694480.1	Gene:	cxadr / 791793	ZFINID:	ZDB-GENE-020814-2	Length:	372	Species:	Danio rerio

Alignment Length:	365	Identity:	73/365 - (20%)
Similarity:	134/365 - (36%)	Gaps:	101/365 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 WLLLLSMVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRV----E 78
            :|.:..::||.|....|..|  :|..|:|..::                 |::..|.|:.    :
Zfish     7 FLCVTYVILLTGSACGLQIT--STGQTSIEKAS-----------------GESVKLDCQFTLASD 52

  Fly    79 RLGDKDVSWI------RKRDLHILTAGGTTYTSDQRFQ-----------VLRPD---GSANWTLQ 123
            ..|..|:.|.      :|.:..::     .|:.|:.|:           ...||   |.|  ::.
Zfish    53 DSGPLDIEWSLQPSDNQKEEKVVI-----VYSGDRAFEHYYDPLKGRVHFNSPDPKNGDA--SMN 110

  Fly   124 IKYPQPRDSGVYECQINTEPKM-SLSYTFNVVELKAEIFGPSDLMVKTGSDINLTCKIMQGPHEL 187
            |...:..|:|.|:|:|...|.: |..|...|:...::....::.....|.::.|.|..::|...:
Zfish   111 IMGLKATDTGTYQCKIKKVPGIASRKYLLTVMVRPSKPKCSAEGQTYVGKNMVLKCSSVEGTQPM 175

  Fly   188 GNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPTVAK--- 249
            ..| |.:.|       .|::...:|.:       |.:|..:.:|.|....:|.|.|   .||
Zfish   176 EYI-WERTS-------GNKLLPPLAIL-------DKVTGTMTLKNATGDASGTYRC---QAKNRV 222

  Fly   250 -TSSVYVHVIIGEHPAAMQHNSSSNSNSFYCG--ICCMLLSIV------SCCLQHF---YETGCG 302
             |....|.|.|.:.|         |:.....|  ||.:||.|:      .||....   ||....
Zfish   223 GTEECVVEVTITQPP---------NTAGIIAGVIICILLLLILLALILFCCCRARHKKKYEKEIA 278

  Fly   303 YLHAAAALAKSAGLGPPKRATLTTSETGISAAEVAAAAGA 342
            |     .:.:..   ||.::.::|:.:..|.....::.|:
Zfish   279 Y-----EIREDV---PPPKSRVSTARSFTSVGSQRSSLGS 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	23/119 (19%)
		IG_like	60..150	CDD:214653	22/114 (19%)
		IG_like	163..257	CDD:214653	20/97 (21%)
		Ig	174..244	CDD:143165	14/69 (20%)
cxadr	NP_694480.1	V-set	28..141	CDD:284989	26/136 (19%)
		IG_like	32..141	CDD:214653	24/132 (18%)
		I-set	141..233	CDD:254352	22/109 (20%)
		Ig_3	147..220	CDD:290638	17/90 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	286..352		5/25 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910