DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and Btnl4

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_109671.1	Gene:	Btnl4 / 632126	MGIID:	1932036	Length:	586	Species:	Mus musculus

Alignment Length:	274	Identity:	55/274 - (20%)
Similarity:	94/274 - (34%)	Gaps:	91/274 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LLSMVLLRGYNAALAPTPPTTST---TTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGD 82
            |||.|..:.:. ...|:.|..:.   ..|.|.::.|..:                    ||.:
Mouse    22 LLSWVTTQEFR-VFGPSDPIVAAPGGEAILPCSVFPAMN--------------------VENM-- 63

  Fly    83 KDVSWIRKRDLHILTAGGTTYTSDQRFQ------------VLRPD----GSANWTLQIKYPQPRD 131
            :::.|.|.|     .:....:..||..|            :|..|    |:|  .::|...|..|
Mouse    64 EELRWFRSR-----FSEAVLFYRDQEEQKEGQMPGYSQRTLLVKDQFHQGTA--AVRILNVQASD 121

  Fly   132 SGVYECQINTEPKMSLSYTFNVVELK---------AEIFGPSDLMVKTGSDINLTCKIMQGPHEL 187
            ||:|.|..    :..:.|...::|||         ..|.||.|      ..:.:.| :..|
Mouse   122 SGIYICHF----QQGVFYDEAILELKVAAMGSVPEVHIKGPED------GGVCVVC-MTSG---- 171

  Fly   188 GNIFWYKGSEM--LDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPTVAKT 250
                ||...::  .|.:||| :.:..:....:|  .:||.|...:.........|.||
Mouse   172 ----WYPEPQVHWKDSRGEN-LTAFSSETHTKD--AEGLFSTETLLVVRDSSVRNVTC------- 222

  Fly   251 SSVYVHVIIGEHPA 264
             |:: :.|:|:..|
Mouse   223 -SIF-NPILGQEKA 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	20/110 (18%)
		IG_like	60..150	CDD:214653	19/105 (18%)
		IG_like	163..257	CDD:214653	18/95 (19%)
		Ig	174..244	CDD:143165	14/71 (20%)
Btnl4	NP_109671.1	Ig	45..145	CDD:386229	26/132 (20%)
		Ig	<167..233	CDD:386229	18/86 (21%)
		SPRY_PRY_C-I_1	344..497	CDD:293968
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910