DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr1 and Btnl6

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_109672.1	Gene:	Btnl6 / 624681	MGIID:	1932038	Length:	539	Species:	Mus musculus

Alignment Length:	248	Identity:	51/248 - (20%)
Similarity:	86/248 - (34%)	Gaps:	73/248 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LLSMVLLRGYNAALAPTPPTTST---TTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGD 82
            |||.|..:.:. ...|:.|..:.   ..|.|.:::|..:                    ||.:
Mouse    22 LLSWVTTKEFQ-VFGPSDPIVAAPGGEAILPCSVIPAMN--------------------VENM-- 63

  Fly    83 KDVSWIRKRDLHILTAGGTTYTS------------DQRFQVLRP---DGSANWTLQIKYPQPRDS 132
            :::.|.|.|    .:|....|..            .||..:::.   .|:|  .::|...|..||
Mouse    64 EELRWFRSR----FSAAVLVYRDQEEQKREQLPEYSQRTSLVKEQFHQGTA--AVRILNVQAPDS 122

  Fly   133 GVYECQINTEPKMSLSYTFNVVELKAEIFGP-SDLMVKTGSD--INLTCKIMQGPHELGNIFWYK 194
            |:|.|..    |..:.|...::|||....|. .::.:|...|  :.:.| |..|        ||.
Mouse   123 GIYICHF----KQGVFYEEAILELKVAAMGSVPEVYIKGPEDGGVCVVC-ITSG--------WYP 174

  Fly   195 GSEM--LDGKGENEIDSSMARIRVEDDWTDGL--TSRLKIKRAMPGDTGNYTC 243
            ..::  .|.:||    ...|.:.:..:...||  |....:.|  .....|.||
Mouse   175 EPQVHWKDSRGE----KLTASLEIHSEDAQGLFRTETSLVVR--DSSVRNVTC 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	20/109 (18%)
		IG_like	60..150	CDD:214653	19/104 (18%)
		IG_like	163..257	CDD:214653	18/88 (20%)
		Ig	174..244	CDD:143165	16/74 (22%)
Btnl6	NP_109672.1	Ig	45..145	CDD:386229	26/131 (20%)
		Ig	150..232	CDD:386229	18/87 (21%)
		SPRY_PRY_C-I_1	341..503	CDD:293968
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910