DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr1 and dscama

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	208	Identity:	53/208 - (25%)
Similarity:	83/208 - (39%)	Gaps:	49/208 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VGQTGF--LHCRVERLGDKDVSWI----------RKRDLHILTAGGTTYTSDQRFQVLRPDGSAN 119
            ||...|  |.|.|:......::|.          |.|.:|.:||.|...:
Zfish   419 VGPNDFVSLTCHVKGTPQPAITWTLDDEVVAKDSRHRIVHSITAEGNVVS--------------- 468

  Fly   120 WTLQIKYPQPRDSGVYECQINTEPKMSLSYTFNV-VELKAEIFGPSDLMVKTGSDINLTCKIMQG 183
             .|.|.:.|.||||||.|..|.... ::||...: |...|:|....:|....|.|:.:.|.::..
Zfish   469 -YLNISHIQVRDSGVYRCTCNNSAG-TVSYQARINVRGSADIRPMKNLTAIAGWDMYIHCHVIGY 531

  Fly   184 PHELGNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTC----V 244
            |:.  :|.|:|.|.:|....         |.|..::  :|....|.:::.:  |.|.|:|    .
Zfish   532 PYY--SIKWFKNSNLLPFND---------RQRAFEN--NGTLKLLNVQKEL--DEGEYSCHVQVQ 581

  Fly   245 PTVAKTSSVYVHV 257
            |.:.|..||:|.|
Zfish   582 PQLFKNQSVHVTV 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	26/99 (26%)
		IG_like	60..150	CDD:214653	25/94 (27%)
		IG_like	163..257	CDD:214653	23/97 (24%)
		Ig	174..244	CDD:143165	15/73 (21%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352
		IG_like	321..402	CDD:214653
		I-set	408..502	CDD:333254	26/99 (26%)
		IGc2	524..579	CDD:197706	15/69 (22%)
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810