DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and igsf9ba

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	263	Identity:	61/263 - (23%)
Similarity:	103/263 - (39%)	Gaps:	61/263 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GWLLLLSMVLLRGYNA--------ALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFL 73
            ||.....::|.:.|:.        .....|||.|.|.              |:.:....|.:..|
Zfish   109 GWYECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTP--------------PQYVEAREGGSITL 159

  Fly    74 HCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQ 138
            .|.........|:|:|:         |...||.:::.|  .|||    |.::.....|.|.|.|:
Zfish   160 TCTAFGNPKPVVTWLRE---------GDQLTSTRKYTV--SDGS----LTVQAITREDRGAYSCR 209

  Fly   139 INTEPKMSLSYTFNVVELKAEIF-GPSDLMVKTGSDINLTCKIMQGPHELGNI--FWYKGSEMLD 200
            .:::...:|..|..:|:....|. .|.::.|....:...||:....|   ||:  .||...:.:.
Zfish   210 AHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYP---GNLTYTWYWEEDNVY 271

  Fly   201 GKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPT----VAKTSSVYVHVIIGE 261
            .|.:.::     |:|:..|.|      |.|.|..|.|.|.|||.|:    ::.::|.|:.|   :
Zfish   272 FKNDLKL-----RVRIFIDGT------LIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTV---Q 322

  Fly   262 HPA 264
            :||
Zfish   323 YPA 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	21/94 (22%)
		IG_like	60..150	CDD:214653	20/89 (22%)
		IG_like	163..257	CDD:214653	26/99 (26%)
		Ig	174..244	CDD:143165	20/71 (28%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	2/5 (40%)
		I-set	139..225	CDD:254352	25/114 (22%)
		I-set	229..321	CDD:333254	27/105 (26%)
		Ig	345..415	CDD:325142
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810