DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and paplna

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	286	Identity:	69/286 - (24%)
Similarity:	98/286 - (34%)	Gaps:	58/286 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHI 95
            ||.::....:.|.|:.|.|.    |:.|....:....|||..|.|.|     ..||.|....:|.
Zfish   927 NAGISEVDSSQSYTSQSSSR----FNIDYSPLVEARAGQTAKLQCSV-----LPVSAIHAVTIHW 982

  Fly    96 LTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQINTEPKMSLSYTFNVVELKAEI 160
            ..||       |....||....::.||.||.....|||:|.|.:....|      |...:::..:
Zfish   983 SRAG-------QPLNSLRHSQHSDGTLVIKQLTADDSGLYTCTVTDAQK------FEERQVQLRV 1034

  Fly   161 FG-------PSDLMVKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSMARIRVED 218
            .|       |.|:.|..||...|.| ::.|  |..|:.|.:....:...|.        |:.|..
Zfish  1035 LGDLRITKAPIDVDVVQGSTAQLAC-VVTG--ENVNVGWSRNGVPVRPDGH--------RVHVSA 1088

  Fly   219 DWTDGLTSRLKIKRAMPGDTGNYTCVPTVAKTSSVYVHVIIGEHPAAMQHNSSSNSNSFYCGIC- 282
            |.|      |.:......|.|.|||   .|.|.::.|.. ..|...|.......:...|....|
Zfish  1089 DGT------LILNNVQSVDEGTYTC---NAYTGTLSVSA-AAEIRLAKTPQQDIDGGQFSSSDCV 1143

  Fly   283 -------CMLLSIVSCCLQHFYETGC 301
                   |.|:.....|...:|.:.|
Zfish  1144 DQPELANCKLIVYARLCSSPYYSSFC 1169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	26/94 (28%)
		IG_like	60..150	CDD:214653	25/89 (28%)
		IG_like	163..257	CDD:214653	25/93 (27%)
		Ig	174..244	CDD:143165	16/69 (23%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449
		IGc2	960..1022	CDD:197706	24/73 (33%)
		I-set	1039..1121	CDD:333254	25/102 (25%)
		PLAC	1142..1173	CDD:312271	6/28 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900