DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and sdk1a

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_009297968.1	Gene:	sdk1a / 558391	ZFINID:	ZDB-GENE-081104-374	Length:	2245	Species:	Danio rerio

Alignment Length:	339	Identity:	78/339 - (23%)
Similarity:	119/339 - (35%)	Gaps:	70/339 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 TTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQR 108
            |:::|:...|      |.::|||.|......|||.......:.|  :||..||.:|....   .|
Zfish   506 TSMAPAFTAP------PLDITVTDGAVAAFTCRVSGAPKPAIVW--RRDTQILASGSVQI---PR 559

  Fly   109 FQVLRPDGSANWTLQIKYPQPRDSGVYEC-QINTEPKMSLSYTFNVVELKAEIFGPSDLMVKTGS 172
            |.:|...|     |||:....:|:|.|.| ..|:|..::.|.:..|....:....|:|..|..|:
Zfish   560 FTLLESGG-----LQIQPVVLQDTGNYTCYAANSEGAINASASLTVWSRTSISSPPTDRRVIKGT 619

  Fly   173 DINLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGD 237
            ...|.|.....|.......|.|..|::.......|......:.:...|:              ||
Zfish   620 TAILECGATHDPRVGVRYVWKKDEELVSHSRGGRISLQEGSLHISQTWS--------------GD 670

  Fly   238 TGNYTC-VPTVAKTSSVYVHVIIGEHPAAMQH-NSSSNSNSFYCGICCMLLSIVSCCLQHFYETG 300
            .||||| |.:.|...|....:.:.|.|.:.:: .:|.|:|.         ...|.......::..
Zfish   671 IGNYTCDVISEAGNESKEARLEVIELPHSPRNLQASLNAND---------SRSVDLSWMRPFDGN 726

  Fly   301 CGYLHAAAALAKSAGLGPPKRATLT---TSETGISAAEVAAAAGASAAVASALATCN-------- 354
            ...||....|:::   ..|.|..|:   .|.||      |...|.:.|.:.....|.
Zfish   727 SPLLHYVVELSEN---NSPWRVYLSDVDPSGTG------AMVKGLTPARSYQFRVCAVNQVGRGQ 782

  Fly   355 --------MLRERP 360
                    ||||.|
Zfish   783 YSTETNRLMLREEP 796

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	28/95 (29%)
		IG_like	60..150	CDD:214653	28/90 (31%)
		IG_like	163..257	CDD:214653	22/94 (23%)
		Ig	174..244	CDD:143165	15/70 (21%)
sdk1a	XP_009297968.1	I-set	125..208	CDD:254352
		Ig	125..204	CDD:299845
		IG_like	222..302	CDD:214653
		Ig	236..287	CDD:299845
		Ig_3	322..394	CDD:290638
		I-set	323..412	CDD:254352
		I-set	416..505	CDD:254352
		Ig	436..500	CDD:299845
		I-set	510..600	CDD:254352	30/105 (29%)
		Ig	527..600	CDD:299845	23/82 (28%)
		I-set	605..693	CDD:254352	22/101 (22%)
		Ig	610..693	CDD:299845	22/96 (23%)
		FN3	697..788	CDD:238020	18/108 (17%)
		fn3	800..886	CDD:278470
		FN3	901..997	CDD:238020
		FN3	1002..1090	CDD:238020
		FN3	1100..1196	CDD:238020
		FN3	1206..1301	CDD:238020
		FN3	1308..1397	CDD:238020
		FN3	1408..1501	CDD:238020
		FN3	1507..1602	CDD:238020
		FN3	1616..1722	CDD:238020
		FN3	1732..1825	CDD:238020
		FN3	1830..1919	CDD:238020
		FN3	1931..2021	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810