DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr1 and kdr

DIOPT Version :9

Sequence 1:NP_001286645.1 Gene:dpr1 / 2768858 FlyBaseID:FBgn0040726 Length:367 Species:Drosophila melanogaster
Sequence 2:NP_001019824.2 Gene:kdr / 554230 ZFINID:ZDB-GENE-041001-112 Length:1357 Species:Danio rerio


Alignment Length:246 Identity:50/246 - (20%)
Similarity:82/246 - (33%) Gaps:88/246 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 FDVPRNLTVTV--------GQTGFLHCRVERLGDKDVSWIRKRDL------------------HI 95
            |.|.|.|.::|        ||...:.|..:||...::.|.|..::                  |:
Zfish   553 FQVTRFLNLSVLPSSSPIEGQDVIMRCVADRLLYYNLRWYRVANVANHDPPPAAVPCDTLTLSHL 617

  Fly    96 ----LTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQP--RDSGVYECQ---INTEPKMSLSYTF 151
                :|..|...|              |.||.:..|..  .|.|:|.||   :.|..|..|.:..
Zfish   618 HQPNVTVSGLQGT--------------NVTLDMPIPNATMMDQGLYACQVEIVGTNEKTCLLHNL 668

  Fly   152 NV--VELKAEIFGPSDLMVKTGSDINLTCKIMQGPHELGNIFWYKGSE-MLDGKG-----ENEI- 207
            .:  :|:...:...:|..|.......|.|::...|  ...|.|.|.:: :::|.|     .|.: 
Zfish   669 RLRALEMSRIVTNLTDQRVNVSDSTTLVCEVSGTP--TPTIVWTKDNQTVMEGSGVILKRSNRVL 731

  Fly   208 -----------------------DSSMARIRVEDDWTDGLTSRLKIKRAMP 235
                                   :||.|||.|     ||...::.::..||
Zfish   732 TIQRVKKEDSGLYICTACNQQGCESSEARISV-----DGAEEKMNVELIMP 777

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr1NP_001286645.1 Ig 59..154 CDD:299845 27/131 (21%)
IG_like 60..150 CDD:214653 26/124 (21%)
IG_like 163..257 CDD:214653 21/103 (20%)
Ig 174..244 CDD:143165 19/92 (21%)
kdrNP_001019824.2 Ig_2 143..221 CDD:290606
IG_like 233..331 CDD:214653
Ig 241..335 CDD:299845
IG_like 345..429 CDD:214653
Ig2_VEGFR-2 356..429 CDD:143272
IG 571..654 CDD:214652 20/96 (21%)
Ig 571..654 CDD:299845 20/96 (21%)
I-set 677..763 CDD:254352 16/87 (18%)
IGc2 691..753 CDD:197706 9/63 (14%)
PKc_like 835..1178 CDD:304357
Pkinase_Tyr 843..1171 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 944..975
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1296..1357
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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