DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr1 and KIRREL1

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_005245362.1	Gene:	KIRREL1 / 55243	HGNCID:	15734	Length:	773	Species:	Homo sapiens

Alignment Length:	271	Identity:	62/271 - (22%)
Similarity:	95/271 - (35%)	Gaps:	74/271 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LIGWLLLLSMVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVER 79
            |:.|:|.||....:|            :.|..|..          |.:.||..||...|.|.:..
Human     4 LLVWILTLSDTFSQG------------TQTRFSQE----------PADQTVVAGQRAVLPCVLLN 46

  Fly    80 LGDKDVSWIRKRDLHILTAG-GTTYTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQINTEP 143
            ... .|.|.:..    |..| |....:..|::|:....:..:.|:|...:..|...||||. ||.
Human    47 YSG-IVQWTKDG----LALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQA-TEA 105

  Fly   144 KM---SLSYTFNVVELKAEIFGPSDLMVKTGSDINLTCKIMQGPHELGNIFWYK----------G 195
            .:   ....|..:......|.|...::::.|:..||||:.... .....|.|::          .
Human   106 ALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFNA-KPAATIIWFRDGTQQEGAVAS 169

  Fly   196 SEML-DGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTC------VPTVAKTS-S 252
            :|:| |||.|..:  |...|...|         |.|.|.       :||      :|:..:|| .
Human   170 TELLKDGKRETTV--SQLLINPTD---------LDIGRV-------FTCRSMNEAIPSGKETSIE 216

  Fly   253 VYVHVIIGEHP 263
            :.||     ||
Human   217 LDVH-----HP 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	24/98 (24%)
		IG_like	60..150	CDD:214653	23/93 (25%)
		IG_like	163..257	CDD:214653	25/111 (23%)
		Ig	174..244	CDD:143165	20/86 (23%)
KIRREL1	XP_005245362.1	I-set	22..116	CDD:254352	24/109 (22%)
		Ig	25..116	CDD:299845	23/106 (22%)
		Ig2_KIRREL3-like	138..219	CDD:143236	23/99 (23%)
		I-set	223..304	CDD:254352	62/271 (23%)
		Ig_2	227..305	CDD:290606
		Ig_2	311..405	CDD:290606
		IG_like	314..405	CDD:214653
		Ig5_KIRREL3	407..504	CDD:143306
		IG_like	416..504	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810