DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr1 and NTM

DIOPT Version :9

Sequence 1:NP_001286645.1 Gene:dpr1 / 2768858 FlyBaseID:FBgn0040726 Length:367 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:232 Identity:52/232 - (22%)
Similarity:91/232 - (39%) Gaps:46/232 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 IGWLL---LLSMVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRV 77
            |.|.:   |.::.|.:|.        |..|.....|..:         .|:||..|::..|.|.:
Human    12 ISWAIFTGLAALCLFQGV--------PVRSGDATFPKAM---------DNVTVRQGESATLRCTI 59

  Fly    78 ERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQINTE 142
            :....: |:|:.:..  ||.||...:..|.|. ||..:....::::|:.....|.|.|.|.:.|:
Human    60 DNRVTR-VAWLNRST--ILYAGNDKWCLDPRV-VLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTD 120

  Fly   143 PKMSLSYTFNVVELKAEIFG-PSDLMVKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDGKGENE 206
            .....|....:|::..:|.. .||:.:..|::|:||| |..|..| ..:.|            ..
Human   121 NHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTC-IATGRPE-PTVTW------------RH 171

  Fly   207 IDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTC 243
            |.........||::       |:|:......:|:|.|
Human   172 ISPKAVGFVSEDEY-------LEIQGITREQSGDYEC 201

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr1NP_001286645.1 Ig 59..154 CDD:299845 23/94 (24%)
IG_like 60..150 CDD:214653 23/89 (26%)
IG_like 163..257 CDD:214653 19/81 (23%)
Ig 174..244 CDD:143165 16/70 (23%)
NTMNP_001338930.1 Ig 44..132 CDD:416386 23/91 (25%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 2/6 (33%)
Ig strand C 64..70 CDD:409353 2/6 (33%)
CDR2 71..83 CDD:409353 4/13 (31%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 9/34 (26%)
Ig strand D 87..94 CDD:409353 3/7 (43%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 1/8 (13%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 20/87 (23%)
Ig strand A' 142..147 CDD:409353 2/4 (50%)
Ig strand B 153..160 CDD:409353 5/7 (71%)
Ig strand C 166..171 CDD:409353 1/16 (6%)
Ig strand D 177..180 CDD:409353 0/2 (0%)
Ig strand E 184..190 CDD:409353 2/12 (17%)
Ig strand F 197..204 CDD:409353 3/5 (60%)
Ig strand G 211..219 CDD:409353
Ig_3 222..299 CDD:404760
putative Ig strand A 223..229 CDD:409353
Ig strand B 239..243 CDD:409353
Ig strand C 252..256 CDD:409353
Ig strand E 278..282 CDD:409353
Ig strand F 292..297 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.