DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and Gm1123

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001074245.1	Gene:	Gm1123 / 382097	MGIID:	2685969	Length:	390	Species:	Mus musculus

Alignment Length:	291	Identity:	66/291 - (22%)
Similarity:	102/291 - (35%)	Gaps:	77/291 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 MVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRV----ERLGDKD 84
            ||.|.|:......|....|.:..:|.           :.:....|:|..|.|..    |..|..|
Mouse     1 MVFLLGFLFLCGVTDHIGSVSITTPE-----------QTIQEVQGETVHLPCMFTLSPEDQGPLD 54

  Fly    85 VSWIR-------KRDLHILTAGGTTYTSDQRFQVLRPD--GSANWT----------LQIKYPQPR 130
            :.|:|       ..| |::    ..|..|:.:.....|  |..|:|          ::|:..||.
Mouse    55 IEWLRLSGPNNEAMD-HVI----ILYAVDKIYSDFYQDMRGRVNFTSNGITSGEASIKIRDVQPA 114

  Fly   131 DSGVYECQINTEP---KMSLSYTFNVVEL--KAEIFGPSDLMVK-TGSDINLTCKIM-----QGP 184
            |||.|.|::.|.|   |.::..|  ||:.  ...|..|...:.| .|..::|.|...     |||
Mouse   115 DSGTYLCKVKTAPGVAKTTVQLT--VVDYIGSVSITTPEQTIEKDQGETVHLPCMFTFISKDQGP 177

  Fly   185 HELGNIFWYKGSEMLDGKGENEIDSSM---ARIRVEDDWTDGLTSR--------------LKIKR 232
            .   ||.|.:    |.|.....:|..:   :..::.||....|..|              :.|..
Mouse   178 L---NIEWLR----LSGPNNEAMDHVVILYSADKIHDDVYPDLKGRVYFTSNDIKSGDASINITN 235

  Fly   233 AMPGDTGNYTC-VPTVAKTSSVYVHVIIGEH 262
            ....|.|.|.| |.|...|.:..:.:.:.:|
Mouse   236 VQLSDAGTYQCKVKTYPGTVNRNLQLAVTDH 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	29/120 (24%)
		IG_like	60..150	CDD:214653	28/115 (24%)
		IG_like	163..257	CDD:214653	26/117 (22%)
		Ig	174..244	CDD:143165	20/92 (22%)
Gm1123	NP_001074245.1	V-set	24..139	CDD:284989	30/132 (23%)
		IG_like	25..138	CDD:214653	30/130 (23%)
		V-set	149..264	CDD:284989	26/121 (21%)
		IG_like	152..263	CDD:214653	25/117 (21%)
		V-set	274..389	CDD:284989
		IG_like	277..388	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910