DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and rst

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	65/319 - (20%)
Similarity:	110/319 - (34%)	Gaps:	95/319 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 PYFDFD------VPRNLTVTVGQTGFLHCRV-ERLGDKDVSWIR-------KRDLHILTAGGTTY 103
            ||..:.      .|::.|..||....|.||| .:.|  .:.|.:       .|||
  Fly    21 PYTSYQNQRFAMEPQDQTAVVGARVTLPCRVINKQG--TLQWTKDDFGLGTSRDL---------- 73

  Fly   104 TSDQRFQVLRPDGSANWTLQIKYPQPRDSGV-YECQINTEP--KMSLSYTFNVVELKAEIFGPSD 165
            :..:|:.::..|...:::|.| ||...|... |:||::..|  :.::..||..:.:......|
  Fly    74 SGFERYAMVGSDEEGDYSLDI-YPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAP-- 135

  Fly   166 LMVKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKI 230
                         ||.|     |::.:  .:|  |.|.|.|..|...:...|..|.|||.:.|.
  Fly   136 -------------KITQ-----GDVIY--ATE--DRKVEIECVSVGGKPAAEITWIDGLGNVLT- 177

  Fly   231 KRAMPGDTGNYTCVPT------VAKTSSVYVHVIIGEHPAAMQHNSSSNSNSFYCGICCMLLSIV 289
                  |...||.:|.      .||:       ::...|....||::                 .
  Fly   178 ------DNIEYTVIPLPDQRRFTAKS-------VLRLTPKKEHHNTN-----------------F 212

  Fly   290 SCCLQHFYETGCGYLHAAAALAKSAGLGPPKRATLTTSETGISAAEVAAAAGASAAVAS 348
            ||..|:..:.    .:.:|.:.......|..:..:..|..|.:...|..|.|.|..:::
  Fly   213 SCQAQNTADR----TYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMST 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	26/105 (25%)
		IG_like	60..150	CDD:214653	24/100 (24%)
		IG_like	163..257	CDD:214653	23/99 (23%)
		Ig	174..244	CDD:143165	19/69 (28%)
rst	NP_001284835.1	IG_like	34..130	CDD:214653	26/108 (24%)
		Ig	42..114	CDD:299845	20/84 (24%)
		C2-set_2	135..225	CDD:285423	29/148 (20%)
		Ig_3	265..329	CDD:290638	0/3 (0%)
		I-set	346..420	CDD:254352
		Ig	360..425	CDD:299845
		Ig5_KIRREL3-like	428..524	CDD:143235
		IG_like	435..524	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810