DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and Igsf10

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_038958192.1	Gene:	Igsf10 / 310448	RGDID:	735030	Length:	2647	Species:	Rattus norvegicus

Alignment Length:	340	Identity:	72/340 - (21%)
Similarity:	119/340 - (35%)	Gaps:	106/340 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 FDVPRNLTVTVGQTGFLHCRVERLGD--KDVSWIRKRDLHILTAGGTTYTSDQRFQVLRPDGSAN 119
            |.||.|..|      ||.|  |.:||  ..:.|.|......::.|    |...||.|| |:|
  Rat  1682 FTVPANSDV------FLPC--EAVGDPLPIIHWTRVSSGLEISQG----TQKSRFHVL-PNG--- 1730

  Fly   120 WTLQIKYPQPRDSGVYECQINTEPKMS-LSYTFNVVELKAEIFG--PSDLMVKTGSDINLTCKIM 181
             ||.|:....:|.|.|.|..:....:. |..:.:||...|.|..  ..::.|.:||.:.|.|::.
  Rat  1731 -TLSIQRVSIQDRGQYLCSASNPLGVDHLHVSLSVVSYPARILDRHVKEITVHSGSTVELKCRVE 1794

  Fly   182 QGPHELGNIFWYKGSEML---DGKGENEI-------------------------------DSSMA 212
            ..|..  .:.|...::.:   ..||..::                               ||.:.
  Rat  1795 GMPRP--TVSWILANQTVVSETAKGSRKVWVTPDGTLIIYNLSLYDRGFYKCVASNPSGQDSLLV 1857

  Fly   213 RIRVEDDWTDGLTSRLKI----KRAMPGDTGNYTCVPTVAK-TSSVYVHVIIGE----HPAAMQH 268
            :|:|       :|:...|    ::|:.|..|....:|..|| |....||.::.:    .|..:.|
  Rat  1858 KIQV-------ITAPPVIIEQKRQAIVGVLGGSLKLPCTAKGTPQPSVHWVLYDGTELKPLQLTH 1915

  Fly   269 NSSSNSNSFYCGICCMLLSIVSCCLQHFYETGCGYLHAAA--------ALAKSAGLGPPKRATLT 325
                  :.|:                 .|..|..|:.:.|        .:|.|:. |..:|..:.
  Rat  1916 ------SRFF-----------------LYPNGTLYIRSIAPSVRGTYECIATSSS-GSERRVVIL 1956

  Fly   326 TSETGISAAEVAAAA 340
            |.|.|.:...:..|:
  Rat  1957 TVEEGETIPRIETAS 1971

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	28/97 (29%)
		IG_like	60..150	CDD:214653	27/92 (29%)
		IG_like	163..257	CDD:214653	23/132 (17%)
		Ig	174..244	CDD:143165	15/107 (14%)
Igsf10	XP_038958192.1	LRRNT	78..110	CDD:214470
		leucine-rich repeat	89..108	CDD:275380
		leucine-rich repeat	109..132	CDD:275380
		LRR_8	131..191	CDD:404697
		leucine-rich repeat	133..156	CDD:275380
		leucine-rich repeat	157..180	CDD:275380
		LRR_8	180..245	CDD:404697
		leucine-rich repeat	181..204	CDD:275380
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..260	CDD:275380
		PCC	242..>323	CDD:188093
		LRRCT	269..>293	CDD:214507
		Ig	532..605	CDD:416386
		Ig strand A'	534..537	CDD:409353
		Ig strand B	543..550	CDD:409353
		Ig strand C	556..562	CDD:409353
		Ig strand C'	564..566	CDD:409353
		Ig strand D	577..581	CDD:409353
		Ig strand E	584..589	CDD:409353
		Ig strand F	597..605	CDD:409353
		IG	632..712	CDD:214652
		Herpes_BLLF1	<1189..1500	CDD:282904
		Ig	1690..1763	CDD:416386	25/89 (28%)
		Ig strand B	1690..1694	CDD:409353	3/9 (33%)
		Ig strand C	1703..1707	CDD:409353	0/3 (0%)
		Ig strand E	1730..1734	CDD:409353	3/7 (43%)
		Ig strand F	1744..1749	CDD:409353	2/4 (50%)
		Ig strand G	1758..1761	CDD:409353	1/2 (50%)
		Ig	1768..1861	CDD:416386	14/94 (15%)
		Ig strand A	1768..1771	CDD:409353	1/2 (50%)
		Ig strand A'	1776..1780	CDD:409353	0/3 (0%)
		Ig strand B	1786..1795	CDD:409353	2/8 (25%)
		Ig strand C	1800..1805	CDD:409353	1/4 (25%)
		Ig strand C'	1808..1810	CDD:409353	0/1 (0%)
		Ig strand D	1819..1822	CDD:409353	0/2 (0%)
		Ig strand E	1827..1834	CDD:409353	0/6 (0%)
		Ig strand F	1840..1848	CDD:409353	0/7 (0%)
		Ig strand G	1851..1861	CDD:409353	3/9 (33%)
		Ig_3	1865..1944	CDD:404760	17/101 (17%)
		Ig strand A	1866..1869	CDD:409353	0/2 (0%)
		Ig strand A'	1875..1878	CDD:409353	1/2 (50%)
		Ig strand B	1884..1891	CDD:409353	1/6 (17%)
		Ig strand C	1897..1903	CDD:409353	2/5 (40%)
		Ig strand C'	1909..1911	CDD:409353	0/1 (0%)
		Ig strand D	1917..1922	CDD:409353	1/21 (5%)
		Ig strand E	1924..1928	CDD:409353	1/3 (33%)
		Ig strand F	1937..1945	CDD:409353	1/7 (14%)
		Ig strand G	1948..1958	CDD:409353	2/9 (22%)
		Ig_3	1965..2044	CDD:404760	1/7 (14%)
		putative Ig strand B	1980..1990	CDD:409353
		putative Ig strand C	1996..2002	CDD:409353
		putative Ig strand D	2018..2021	CDD:409353
		putative Ig strand E	2023..2029	CDD:409353
		putative Ig strand F	2036..2044	CDD:409353
		IG_like	2077..2160	CDD:214653
		Ig strand B	2078..2085	CDD:409353
		Ig strand C	2093..2097	CDD:409353
		Ig strand D	2122..2125	CDD:409353
		Ig strand E	2126..2131	CDD:409353
		Ig strand F	2139..2147	CDD:409353
		Ig strand G	2153..2160	CDD:409353
		IG	2178..2252	CDD:214652
		IG_like	2283..2354	CDD:214653
		Ig strand C	2294..2298	CDD:409353
Ig strand E	2320..2324	CDD:409353
Ig strand F	2334..2339	CDD:409353
Ig_3	2360..2439	CDD:404760
Ig strand B	2379..2383	CDD:409353
Ig strand C	2392..2396	CDD:409353
Ig strand E	2418..2422	CDD:409353
Ig strand F	2432..2437	CDD:409353
Ig_3	2455..2534	CDD:404760
Ig_3	2551..2633	CDD:404760
Ig strand A	2552..2555	CDD:409353
Ig strand A'	2561..2564	CDD:409353
Ig strand B	2570..2577	CDD:409353
Ig strand C	2583..2591	CDD:409353
Ig strand C'	2596..2598	CDD:409353
Ig strand D	2604..2610	CDD:409353
Ig strand E	2612..2616	CDD:409353
Ig strand F	2625..2633	CDD:409353
Ig strand G	2636..2646	CDD:409353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910