DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001100667.1	Gene:	Igsf9 / 304982	RGDID:	1304566	Length:	1179	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	74/334 - (22%)
Similarity:	118/334 - (35%)	Gaps:	105/334 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LLLLSMVLLRGYNAALAP------------------------TPPTTSTTTISPSNLLPYF-DFD 58
            |.:||::|.:|.:....|                        .||......:....|||.| .|.
  Rat     7 LTILSLILSQGADGRRKPEVVSVVGRAGESAVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFG 71

  Fly    59 V--PRNLTVTVG----QTGFLHCRVERLGDKDVSWIRKRDLHILT-------AGGT----TYTSD 106
            :  ||.....||    ||| ...::|.|..:|..|...|.|.:..       |.|:    |..|.
  Rat    72 LYSPRIDPDYVGRVRLQTG-ASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSP 135

  Fly   107 QRFQ---------------VLR------PDGSANW-------------------TLQIKYPQPRD 131
            .:||               .||      |.....|                   ||.|:..:...
  Rat   136 PQFQETPPLVLEVKELEAVTLRCVALGSPQPYVTWKFRGQDLGKGQGQVQVRNGTLWIRRVERGS 200

  Fly   132 SGVYECQINTEPKMSLSYTFNVVELKAEIF--GPSDLMVKTGSDINLTCKIMQGPHELGNIFWYK 194
            :|.|.||.:: .:.|:::|..::.|...:.  .|::..|....|::|.|:....|..| ...|::
  Rat   201 AGDYTCQASS-TEGSVTHTTQLLVLGPPVIVVPPNNNTVNASQDVSLACRAEAYPANL-TYSWFQ 263

  Fly   195 GSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPTVA----KTSSVYV 255
                 |......|....:|:|:   ..||   .|.::...|.|.|:|||||:..    .::|.|:
  Rat   264 -----DRINVFHISRLQSRVRI---LVDG---SLWLQATQPDDAGHYTCVPSNGFPHPPSASAYL 317

  Fly   256 HVIIGEHPA 264
            .|:   :||
  Rat   318 TVL---YPA 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	32/151 (21%)
		IG_like	60..150	CDD:214653	31/144 (22%)
		IG_like	163..257	CDD:214653	25/97 (26%)
		Ig	174..244	CDD:143165	17/69 (25%)
Igsf9	NP_001100667.1	IG	28..110	CDD:214652	18/82 (22%)
		Ig strand A	136..139	CDD:409353	0/2 (0%)
		IG_like	143..223	CDD:214653	13/80 (16%)
		Ig strand A'	145..148	CDD:409353	0/2 (0%)
		Ig strand B	154..161	CDD:409353	2/6 (33%)
		Ig strand C	167..172	CDD:409353	1/4 (25%)
		Ig strand C'	175..177	CDD:409353	0/1 (0%)
		Ig strand D	183..187	CDD:409353	0/3 (0%)
		Ig strand E	189..193	CDD:409353	2/3 (67%)
		Ig strand F	202..210	CDD:409353	4/7 (57%)
		Ig strand G	213..223	CDD:409353	2/9 (22%)
		Ig_3	226..305	CDD:404760	23/90 (26%)
		putative Ig strand A	226..230	CDD:409353	0/3 (0%)
		putative Ig strand A'	235..239	CDD:409353	0/3 (0%)
		putative Ig strand B	241..251	CDD:409353	3/9 (33%)
		putative Ig strand C'	267..270	CDD:409353	0/2 (0%)
		putative Ig strand D	279..282	CDD:409353	1/5 (20%)
		putative Ig strand E	284..290	CDD:409353	2/8 (25%)
		putative Ig strand F	297..305	CDD:409353	6/7 (86%)
		putative Ig strand G	310..319	CDD:409353	2/8 (25%)
		Ig	322..407	CDD:416386	2/2 (100%)
		Ig strand A'	324..328	CDD:409353	74/334 (22%)
		Ig strand B	333..347	CDD:409353
		Ig strand C	353..359	CDD:409353
		Ig strand C'	362..364	CDD:409353
		Ig strand D	371..374	CDD:409353
		Ig strand E	378..382	CDD:409353
		Ig strand F	391..399	CDD:409353
		Ig	418..503	CDD:416386
		Ig strand A	418..421	CDD:409353
		Ig strand A'	427..430	CDD:409353
		Ig strand B	436..443	CDD:409353
		Ig strand C	449..454	CDD:409353
		Ig strand C'	457..459	CDD:409353
		Ig strand D	462..466	CDD:409353
		Ig strand E	469..473	CDD:409353
		Ig strand F	482..490	CDD:409353
		Ig strand G	493..503	CDD:409353
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	766..807
		PHA03247	<777..1062	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..846
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	869..895
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..979
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding. /evidence=ECO:0000250	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900