DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and ncam1a

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_009293555.1	Gene:	ncam1a / 30447	ZFINID:	ZDB-GENE-990415-31	Length:	1010	Species:	Danio rerio

Alignment Length:	236	Identity:	60/236 - (25%)
Similarity:	79/236 - (33%)	Gaps:	63/236 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 NLLP-----YFDFDVPRNLTVTVGQTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRF 109
            |:||     |.:.    |.|..:.|...|.|..:...:..|.|.|         |.|...||:::
Zfish   206 NVLPSIRTRYTEL----NATADINQAVTLACHADGYPEPTVKWAR---------GNTELESDEKY 257

  Fly   110 QVLRPDGSANWTLQIKYPQPRDSGVYEC-QINTEPKMSLSYTFNVVELKAEIFGPSDLMVKTGSD 173
            . |..|||   .|.||.....|.|.|:| ..|...:.|...|.||.......|..:....:....
Zfish   258 S-LNEDGS---ELTIKDVNKLDEGDYKCIARNKAGERSEEVTLNVFVQPKITFLENQTASELEEQ 318

  Fly   174 INLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSMARIRVEDDWT----------------D 222
            |.|||:....|  ..||.|..|..:..   |||          :..||                |
Zfish   319 ITLTCEATGDP--TPNIIWSFGRRVFT---ENE----------QASWTRPEKHKSLDGNVVVRSD 368

  Fly   223 GLTSRLKIKRAMPGDTGNYTCVPTVAKTS------SVYVHV 257
            ...|.|.:|.....|.|.|.|   .|:.|      |:|:.|
Zfish   369 ARVSSLTLKYVQFTDAGQYLC---TARNSIGQDIQSMYLEV 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	27/95 (28%)
		IG_like	60..150	CDD:214653	25/90 (28%)
		IG_like	163..257	CDD:214653	26/115 (23%)
		Ig	174..244	CDD:143165	21/85 (25%)
ncam1a	XP_009293555.1	Ig	20..112	CDD:299845
		I-set	21..111	CDD:254352
		IG_like	121..200	CDD:214653
		IGc2	128..189	CDD:197706
		Ig	208..301	CDD:299845	31/109 (28%)
		IG_like	219..298	CDD:214653	26/91 (29%)
		Ig	300..406	CDD:299845	27/123 (22%)
		IG_like	308..406	CDD:214653	26/115 (23%)
		ig	413..498	CDD:278476
		IG_like	415..498	CDD:214653
		fn3	505..589	CDD:278470
		FN3	624..715	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900