DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and Tyro3

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_058788.1	Gene:	Tyro3 / 25232	RGDID:	3923	Length:	880	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	70/289 - (24%)
Similarity:	107/289 - (37%)	Gaps:	53/289 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LSMVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGDKDVS 86
            |..:||.|..:.|.|.........:.           .|..:||:.||...|:|.||.:.|.|:.
  Rat    12 LRPLLLAGLASLLLPGSAAAGLKLMG-----------APVKMTVSQGQPVKLNCSVEGMDDPDIH 65

  Fly    87 WIRKRDLHILTAGGTTYTSDQRFQVLRPDGSANW--TLQIKYPQPRDSGVYECQI--NTEPKMSL 147
            |::.        |.....:.   ||.......||  .|.:|..:..|:|:|.||:  ..|.|:|.
  Rat    66 WMKD--------GAVVQNAS---QVSISISEQNWIGLLSLKSAERSDAGLYWCQVKDGEETKISQ 119

  Fly   148 SYTFNVVELKAEIFGPSDLMVKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDGKGENEIDSSMA 212
            |....|..:......|.||.|.......|:|:.: ||.|...|||::|...:.|..     ||.:
  Rat   120 SVWLTVEGVPFFTVEPKDLAVPPNVPFQLSCEAV-GPPEPVTIFWWRGPTKVGGPA-----SSPS 178

  Fly   213 RIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCVPTVAKTSSVYVHVIIGEHPAAMQHN------SS 271
            .:.|     .|:|.|.:.........|..|..|.:.:..:          |.|...|      ||
  Rat   179 VLNV-----TGVTQRTEFSCEAHNIKGLATSRPAIIRLQA----------PPAAPFNITVTTISS 228

  Fly   272 SNSNSFYCGICCMLLSIVSCCLQHFYETG 300
            ||::..:......|..:.||.:|..:..|
  Rat   229 SNASVAWVPGADGLALLHSCTVQVAHAPG 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	28/98 (29%)
		IG_like	60..150	CDD:214653	28/93 (30%)
		IG_like	163..257	CDD:214653	23/93 (25%)
		Ig	174..244	CDD:143165	18/69 (26%)
Tyro3	NP_058788.1	IG_like	39..125	CDD:214653	28/96 (29%)
		IGc2	46..111	CDD:197706	21/75 (28%)
		Ig2_Tyro3_like	131..209	CDD:143226	23/88 (26%)
		IG_like	135..204	CDD:214653	21/79 (27%)
		FN3	215..307	CDD:238020	11/43 (26%)
		fn3	315..396	CDD:278470
		PTKc_Tyro3	498..781	CDD:270659
		Pkinase_Tyr	508..776	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	804..827
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	842..864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910