DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr1 and Ptprq

DIOPT Version :9

Sequence 1:	NP_001286645.1	Gene:	dpr1 / 2768858	FlyBaseID:	FBgn0040726	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001357916.1	Gene:	Ptprq / 237523	MGIID:	1096349	Length:	2301	Species:	Mus musculus

Alignment Length:	327	Identity:	56/327 - (17%)
Similarity:	103/327 - (31%)	Gaps:	107/327 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PPTTSTT----------------TISPSNLLPYFD------------------FDVPRNLTVTVG 68
            |||..|.                .||.|::|.|:|                  .|..|...:|..
Mouse   557 PPTVLTVRTREQVPSSIQIINYKNISSSSILLYWDPPEYPNGKITHYTIYAMELDTNRAFQMTTV 621

  Fly    69 QTGFLHCRVERLGDKDVSWIRKRDLHILTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPR-DS 132
            ...||           ::.::|...:.:....:|:..:...       |....|.::.|:.. :|
Mouse   622 DNSFL-----------ITGLKKYTRYKMRVAASTHVGESSL-------SEENDLFVRTPEDEPES 668

  Fly   133 GVYECQINTEPKMSLSYTF------NVVELKAEIF--GPSDLMVKTGSDINLTCKIMQGPHELGN 189
            ...:.::.......||.|:      |.:.:..|:|  ....|.||..|..|:|...:: |:.|.|
Mouse   669 SPQDVKVTDVSPSELSLTWSPPEKPNGIIIAYEVFYQNADALFVKNTSTTNITLSDLK-PYTLYN 732

  Fly   190 IFWYKGSEMLDGKGENEIDSSMARIRVEDDWTDGLTSRLKIK--------------RAMPGDTGN 240
            |.....:.:    |.....||:..:|..:...|.....:..|              |:..|....
Mouse   733 ISIQSYTRL----GHGNQSSSLLSVRTSETVPDSAPENITYKNISSEEIEIFFLPPRSPNGIIQK 793

  Fly   241 YT------------CVPTVAKTSSV-----YVHVIIGEHPAAMQHNSSSNSNSFYCGICCMLLSI 288
            ||            .:.|.:.|.::     |.|.:|....:.::..          |:..|.:||
Mouse   794 YTIYLKRSNSHEARTIETTSLTLTIGGLKKYTHYVIEVSASTLKGE----------GVRSMPISI 848

  Fly   289 VS 290
            ::
Mouse   849 LT 850

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr1	NP_001286645.1	Ig	59..154	CDD:299845	14/101 (14%)
		IG_like	60..150	CDD:214653	12/90 (13%)
		IG_like	163..257	CDD:214653	23/124 (19%)
		Ig	174..244	CDD:143165	16/95 (17%)
Ptprq	NP_001357916.1	FN3	57..151	CDD:238020
		FN3	308..393	CDD:238020
		fn3	399..>441	CDD:365830
		FN3	570..654	CDD:238020	14/101 (14%)
		fn3	668..744	CDD:365830	18/80 (23%)
		FN3	762..850	CDD:238020	14/97 (14%)
		fn3	857..934	CDD:365830
		FN3	951..1049	CDD:238020
		FN3	1056..1137	CDD:238020
		FN3	1152..1233	CDD:238020
		FN3	1247..1337	CDD:238020
		FN3	1342..1421	CDD:238020
		FN3	1432..1535	CDD:238020
		FN3	1542..1638	CDD:238020
		FN3	1645..1734	CDD:238020
		UP_III_II	1759..1928	CDD:297589
		R-PTPc-Q	2033..2256	CDD:350464
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900